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25728 Apoe

25728

Apoe

apolipoprotein E

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition apolipoprotein E

研究结论

Date Results Publications
2020-02-08 11:27:00 The inhibition of HDAC6 activity was also demonstrated to reduce brain injury induced by APOE4 and Abeta140 coaggregation in model rats. 31432127
2019-09-14 10:09:00 Data demonstrated that mechanical injury of neurons stimulated oligodendrocytes to secrete apoE. The injured neurons could absorb secreted apoE. The expression of apoE contributed to the activation of p38 MAPK, which facilitated neuron repair. 30958617
2019-06-01 10:41:00 Deficiency of either Ldlr or Apoe genes induced hyperlipidemia, which promoted endothelial inflammation and led to typical atherosclerosis in rats on normal or Western diets. 29459263
2019-03-23 11:27:00 After isolation and during maintenance in culture, adherent rat islets reduce expression of key beta-cell transcription factors necessary for beta-cell function and that soluble pancreatic decellularized matrix can enhance beta-cell gene expression. Study identified APOE as an extracellular protein that significantly increased the expression of key beta-cell genes, mediated at least in part through the signali... 30303984
2018-06-23 11:20:00 Infusion of AngII did not lead to the formation of dissecting abdominal aortic aneurysms or atherosclerosis in ApoE-knockout rats. 29166645

名称对应

Type IDs
Synonymous APOEA
Gene
UniProtKB-ID: APOE_RAT
UniprotKB: P02650
UniParc: UPI0000125C57
EMBL: S76779, X04979, J02582, BC086581
Ensembl: ENSRNOG00000018454
KO: rno:25728
Nucleutide sequences
EMBL-CDS: CAA28650.1, AAC60703.1, AAA40755.1, AAH86581.1
Ensembl_TRS: ENSRNOT00000041891, ENSRNOT00000091574
Protein sequencees
Ensembl_PRO: ENSRNOP00000050968, ENSRNOP00000068937
RefSeq: NP_001257612.1, NP_620183.2, NP_001257611.1, NP_001257610.1, NP_001257613.1
Others
UniRef100: UniRef100_P02650
UniRef90: UniRef90_P08226
UniRef50: UniRef50_P08226
UniGene: Rn.32351

全选

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研究热度

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