| Type | Description |
|---|---|
| Definition | germinal center associated signaling and motility |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 18:50:00 | Recent BCR stimulation induces a negative autoregulatory loop via FBXO10 mediated degradation of HGAL. | 31570756 |
| 2020-08-01 10:42:00 | we have demonstrated that Grb2 directly interacts with phosphorylated HGAL, collaborating in cSMAC formation while oppositely regulating BCR-induced intracellular biochemical signaling. These interactions may play an important function in regulating the magnitude of BCR signaling and antigen presentation. | 31362927 |
| 2016-05-14 10:24:00 | Diagnostic Utility of the Germinal Center-associated Markers GCET1, HGAL, and LMO2 in Hematolymphoid Neoplasms. | 25203428 |
| 2015-03-28 13:05:00 | These findings further elucidate the growing and complex role of HGAL in B-cell biology and suggest that membrane-bound and cytoplasmic HGAL protein differently regulates distinct biological processes. | 25381061 |
| 2013-09-28 10:45:00 | HGAL and LMO2 may be useful adjuncts in the identification of follicular lymphoma of the nongastric gastrointestinal tract. | 22914613 |
| Type | IDs |
|---|---|
| Synonymous | GCAT2, GCET2, HGAL |
| Gene |
UniProtKB-ID:
GCSAM_HUMAN
UniprotKB:
Q8N6F7
UniParc:
UPI0001D62837,
UPI000042262E,
UPI000000D7DB
EMBL:
BM456595,
AC128688,
AF521911,
BC030506,
AY212246
Ensembl:
ENSG00000174500,
ENSG00000284925
KO:
hsa:257144
|
| Nucleutide sequences |
EMBL-CDS:
AAH30506.1,
AAO22147.1,
AAO21701.1
Ensembl_TRS:
ENST00000646639,
ENST00000460387,
ENST00000484193,
ENST00000644247,
ENST00000308910,
ENST00000643065
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000494547,
ENSP00000420603,
ENSP00000496265,
ENSP00000493535,
ENSP00000309487,
ENSP00000419485
RefSeq:
XP_011510932.1,
XP_011510929.1,
NP_689998.1,
XP_024309205.1,
XP_024309206.1,
XP_005247329.1,
NP_001177188.1,
NP_001177189.1,
XP_011510931.1,
XP_024309207.1
|
| Others |
UniRef100:
UniRef100_Q8N6F7
UniRef90:
UniRef90_Q8N6F7
UniRef50:
UniRef50_Q8N6F7
UniGene:
Hs.49614
CCDS:
CCDS2964.1,
CCDS54622.1,
CCDS54621.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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