| Type | Description |
|---|---|
| Definition | guanylate cyclase 2C |
| Date | Results | Publications |
|---|---|---|
| 2018-08-04 12:01:00 | These results support the hypothesis that IL-15 secreted from Gn-GC-C-expressing macrophages contributes to the inhibition of fatty acid synthase and lipid accumulation in adipocytes, leading to obesity resistance | 29097254 |
| 2016-08-20 12:24:00 | Data (including data from studies in transgenic rats) suggest guanylin--guanylyl cyclase-C signaling in macrophages in mesenteric fat regulates cGMP--PKG--VASP pathway and mesenteric panniculitis/obesity via down-regulation of proinflammatory factors. | 26249840 |
| 2013-06-01 11:47:00 | the macrophagic guanylin-GC-C system contributes to the altered expression of genes involved in lipid metabolism, leading to resistance to obesity | 23081987 |
| 2011-04-02 10:55:00 | these studies provide a comprehensive description of Ugn and GC-C expression in the kidney of the Sprague-Dawley rat. | 21106860 |
| 2010-01-21 00:00:00 | the role of the linker region in receptor guanylyl cyclases | 19648115 |
| Type | IDs |
|---|---|
| Synonymous | GCC |
| Gene |
UniProtKB-ID:
GUC2C_RAT
UniprotKB:
P23897
UniParc:
UPI000012CCE3
EMBL:
M55636
Ensembl:
ENSRNOG00000009031
KO:
rno:25711
|
| Nucleutide sequences |
EMBL-CDS:
AAA41201.1
Ensembl_TRS:
ENSRNOT00000012212
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000012212
RefSeq:
NP_037302.1
|
| Others |
UniRef100:
UniRef100_P23897
UniRef90:
UniRef90_P23897
UniRef50:
UniRef50_P25092
UniGene:
Rn.10931
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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