| Type | Description |
|---|---|
| Definition | serine incorporator 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | Patient-Derived HIV-1 Nef Alleles Reveal Uncoupling of CD4 Downregulation and SERINC5 Antagonism Functions of the Viral Pathogenesis Factor. | 32541384 |
| 2021-03-20 13:31:00 | An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles. | 32590431 |
| 2021-03-13 13:24:00 | HIV-cell membrane fusion intermediates are restricted by Serincs as revealed by cryo-electron and TIRF microscopy. | 32788212 |
| 2021-03-13 13:17:00 | Nef homodimers down-regulate SERINC5 by AP-2-mediated endocytosis to promote HIV-1 infectivity. | 32873704 |
| 2021-01-09 13:30:00 | Differential Pressures of SERINC5 and IFITM3 on HIV-1 Envelope Glycoprotein over the Course of HIV-1 Infection. | 32493821 |
| Type | IDs |
|---|---|
| Synonymous | C5orf12, TPO1 |
| Gene |
UniProtKB-ID:
SERC5_HUMAN
UniprotKB:
Q86VE9
UniParc:
UPI000018DB0C,
UPI00005764EB,
UPI000004E86E,
UPI000020CBA2
EMBL:
CH471084,
BC101283,
BC101280,
AC012636,
BC101281,
AF498273,
AK297467,
AC010260
Ensembl:
ENSG00000164300
KO:
hsa:256987
|
| Nucleutide sequences |
EMBL-CDS:
EAW95844.1,
AAI01281.1,
AAI01284.1,
EAW95845.1,
BAG59889.1,
AAP06800.1,
AAI01282.1,
EAW95843.1
Ensembl_TRS:
ENST00000512972,
ENST00000509193,
ENST00000507668
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000421665,
ENSP00000426237,
ENSP00000426134
RefSeq:
XP_016864813.1,
NP_840060.1,
XP_016864812.1,
NP_001167542.1,
XP_011541606.1,
XP_024301781.1,
XP_016864815.1,
NP_001167543.1
|
| Others |
UniRef100:
UniRef100_Q86VE9
UniRef90:
UniRef90_Q86VE9
UniRef50:
UniRef50_Q86VE9
UniGene:
Hs.288232
CCDS:
CCDS54874.1,
CCDS83009.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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