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25697 Ctsl

25697

Ctsl

cathepsin L

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition cathepsin L

研究结论

Date Results Publications
2020-04-18 11:00:00 Cathepsin L induces apoptosis in rotenone-treated PC-12 cells via activation of B-Myb protein. 31444477
2020-01-04 12:03:00 The results revealed that cathepsin B and L activity is required for maintenance of a fully differentiated state of thyrocytes featuring Taar1-bearing primary cilia. 31302164
2019-08-03 10:49:00 In contrast to the weak levels of cathepsin L in normal glomeruli, on days 4 and 8, strong immunostaining was detected in almost all podocytes when proteinuria and pathological changes of the podocytes developed. Cathepsin L was reduced after day 28, but remained in a focal and segmental manner. Cystatin B, an intracellular inhibitor, was not detected in podocytes. 30052474
2017-08-26 11:16:00 the activation of cathepsin L contributes to the irreversible depolarization produced by oxygen and glucose deprivation 27818353
2017-07-08 13:14:00 Data indicate the role of a cathepsin-caspase 3 axis in the nuclear translocation of transcription Factor EB (TFEB) leading to lysosome biogenesis under conditions of sub-lethal oxidative stress. 28002813

名称对应

Type IDs
Synonymous CATHL, CatL, Ctsl1
Gene
UniProtKB-ID: CATL1_RAT
UniprotKB: P07154
UniParc: UPI00001270BC
EMBL: AF025476, BC063175, S85184, Y00697
Ensembl: ENSRNOG00000018566
KO: rno:25697
Nucleutide sequences
EMBL-CDS: AAH63175.1, AAB21516.1, CAA68691.1, AAB81616.1
Ensembl_TRS: ENSRNOT00000025462
Protein sequencees
Ensembl_PRO: ENSRNOP00000025462
RefSeq: NP_037288.1
Others
UniRef100: UniRef100_P07154
UniRef90: UniRef90_P06797
UniRef50: UniRef50_P06797
UniGene: Rn.1294

全选

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研究热度

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