| Type | Description |
|---|---|
| Definition | 3-hydroxy-3-methylglutaryl-CoA reductase |
| Date | Results | Publications |
|---|---|---|
| 2018-06-16 10:36:00 | This study is aiming to investigate the inhibition role of quercetin on hydroxy methyl glutarate - CoA reductase activity and its gene for attenuating hypercholesterolemia. | 28938515 |
| 2015-06-06 14:03:00 | findings demonstrate for the first time that strain-dependent sex difference in serum Total Cholesterol level between F344 and SD rats is, at least in part, related to difference in the IL-1alpha-mediated HMGR gene expression level in the liver. | 24694611 |
| 2014-08-09 10:32:00 | HMGCR expression is reduced in the liver of rats exposed to simvaglyzin and atorvaglyzin. | 24319730 |
| 2014-01-25 11:48:00 | Capsaicinoids consumption down-regulated the mRNA levels of HMG-CoA reductase and CYP7A1 in the cholesterol-free diet group but up-regulated the CYP7A1 level in the cholesterol-enriched diet group. | 23617777 |
| 2013-11-16 10:28:00 | investigated 3-hydroxy 3-methylglutaryl coenzyme A reductase and LDLr in adult (3-month-old) and aged (12-month-old) male and female rats in four different brain regions | 23280554 |
| Type | IDs |
|---|---|
| Synonymous | 3H3M |
| Gene |
UniProtKB-ID:
HMDH_RAT
UniprotKB:
P51639
UniParc:
UPI000019BF6D
EMBL:
M29249,
X55286,
BC064654
Ensembl:
ENSRNOG00000016122
KO:
rno:25675
|
| Nucleutide sequences |
EMBL-CDS:
CAA39001.1,
AAA40608.1,
AAH64654.1
Ensembl_TRS:
ENSRNOT00000022055
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000022055
RefSeq:
XP_006231888.1,
NP_037266.2
|
| Others |
UniRef100:
UniRef100_P51639
UniRef90:
UniRef90_P51639
UniRef50:
UniRef50_P04035
UniGene:
Rn.9437
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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