| Type | Description |
|---|---|
| Definition | sodium voltage-gated channel alpha subunit 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 16:01:00 | Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin. | 33397917 |
| 2020-10-24 14:04:00 | Direct and Indirect Suppression of Scn5a Gene Expression Mediates Cardiac Na(+) Channel Inhibition by Wnt Signalling. | 32046907 |
| 2020-06-27 11:12:00 | UBC9 regulates Nav1.5 expression levels in a SUMOylation-independent manner. | 30772377 |
| 2020-06-20 12:42:00 | The analysis for the protein production demonstrated Nup107-facilitated transport of Scn5a mRNA. Using RIP-PCR and luciferase assay, we found that the 5'-UTR of Scn5a mRNA was not involved in the interaction, whereas the spatial interaction between Nup107 protein and Scn5a mRNA was formed when Scn5a mRNA passing through the nuclear pore. | 30506890 |
| 2019-09-21 12:20:00 | The NaV1.5-Kir2.1 macromolecular complex pre-assembles early in the forward trafficking pathway. Therefore, disruption of Kir2.1 trafficking in cardiomyocytes affects trafficking of NaV1.5, which may have important implications in the mechanisms of arrhythmias in inheritable cardiac diseases. | 29514831 |
| Type | IDs |
|---|---|
| Synonymous | Nav1.5, SCAL |
| Gene |
UniProtKB-ID:
SCN5A_RAT,
A0A0G2JWG8_RAT,
F1LPK3_RAT
UniprotKB:
P15389,
A0A0G2JWG8,
F1LPK3
UniParc:
UPI0003D08401,
UPI00001279D0,
UPI00000E5B17,
UPI0000250C03
EMBL:
AC094738,
AF353637,
M27902
Ensembl:
ENSRNOG00000015049
KO:
rno:25665
|
| Nucleutide sequences |
EMBL-CDS:
AAK38884.1,
AAA42114.1
Ensembl_TRS:
ENSRNOT00000082892,
ENSRNOT00000064555
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000069875,
ENSRNOP00000060180
RefSeq:
NP_001153634.2,
XP_017450971.1,
XP_006244138.1,
NP_037257.2,
XP_017450970.1
|
| Others |
UniRef100:
UniRef100_P15389,
UniRef100_A0A0G2JWG8,
UniRef100_F1LPK3
UniRef90:
UniRef90_Q9JJV9
UniRef50:
UniRef50_Q14524
UniGene:
Rn.32074
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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