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2566 GABRG2

2566

GABRG2

gamma-aminobutyric acid type A receptor gamma2 subunit

protein-coding

Homo sapiens

基因描述

Type Description
Definition gamma-aminobutyric acid type A receptor gamma2 subunit

研究结论

Date Results Publications
2021-02-20 13:28:00 Interactions of the GABRG2 polymorphisms and childhood trauma on suicide attempt and related traits in depressed patients. 32056912
2021-01-23 12:59:00 Photoaffinity labeling identifies an intersubunit steroid-binding site in heteromeric GABA type A (GABAA) receptors. 32540960
2018-12-22 10:09:00 high-resolution cryo-electron microscopy structures of the human alpha1beta2gamma2 GABAA receptor, the predominant isoform in the adult brain, in complex with GABA and the benzodiazepine site antagonist flumazenil, the first-line clinical treatment for benzodiazepine overdose 29950725
2018-10-20 12:21:00 Study found that the C588T polymorphism of GABARG2 is associated with an increased risk of developing childhood idiopathic generalized epilepsy and may modulate patients' response to antiepileptic drugs. 29894917
2018-07-21 10:45:00 This study demonstrated that GABRG2 expression in gamma2 in the cortical nuclei, and amygdalo-hippocampal/parahippocampal-amygdala transition areas. 29023704

名称对应

Type IDs
Synonymous CAE2, ECA2, GEFSP3
Gene
UniProtKB-ID: GBRG2_HUMAN
UniprotKB: P18507
UniParc: UPI000013C948, UPI00002263BC, UPI00017503BD
EMBL: AC091984, AF165124, BC069348, BC074795, BC059389, X15376, AC008611, AC091926
Ensembl: ENSG00000113327
KO: hsa:2566
Nucleutide sequences
EMBL-CDS: AAH69348.1, AAD50273.1, CAA33437.1, AAH59389.1, AAH74795.1
Ensembl_TRS: ENST00000639111, ENST00000639213, ENST00000414552
Protein sequencees
Ensembl_PRO: ENSP00000492125, ENSP00000491909, ENSP00000410732
RefSeq: NP_001362272.1, NP_001362279.1, NP_001362268.1, NP_001362275.1, NP_001362271.1, NP_001362278.1, NP_000807.2, NP_001362277.1, NP_001362274.1, NP_001362269.1, NP_001362270.1, NP_944494.1, NP_944493.2, NP_001362273.1, NP_001362276.1
Others
UniRef100: UniRef100_P18507
UniRef90: UniRef90_P18507
UniRef50: UniRef50_P18507
UniGene: Hs.7195
CCDS: CCDS4358.1, CCDS47333.1, CCDS4359.1

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