| Type | Description |
|---|---|
| Definition | adrenoceptor beta 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 11:16:00 | Present data can emphasize the important deleterious effect of beta3 -AR activation in cardiac remodeling under pathological condition, at least, through a cross-link between beta3 -AR activation, NO-signaling, and [Zn(2+) ]i pathways. | 30613975 |
| 2020-05-30 10:46:00 | Voluntary exercise induced opposite changes in the gene expression of beta3-adrenergic receptors in the white and in the brown adipose tissue. | 31295748 |
| 2018-12-01 11:34:00 | In heart failure, the expression of cardiac beta3-adrenergic receptors (beta3-ARs) increases. However, the precise role of beta3-AR signaling within cardiomyocytes remains unclear. The beta3-AR activation in cardiomyocytes increases the expression of TGFbeta1 via the PKG/JNK/c-Jun pathway. | 29859189 |
| 2018-11-10 11:14:00 | Study demonstrates that MRI allows a precocious detection of the subtle myocardial dysfunction induced by beta1-adrenoreceptors-autoantibodies (beta1-aabs) and that beta3-adrenoreceptor stimulation blunts the development of beta1-aabs-induced dilated cardiomyopathy. | 28276515 |
| 2018-11-03 11:53:00 | Increasing beta3-AR stimulation may prevent the consequences of chronic NA exposure on Na(+)/K(+) pump and in vivo hemodynamics. beta3-AR agonism may thus represent a new therapeutic strategy for pharmacological modulation of hypertrophy under conditions of chronically enhanced sympathetic activity. | 29363058 |
| Type | IDs |
|---|---|
| Synonymous | ADRB |
| Gene |
UniProtKB-ID:
ADRB3_RAT
UniprotKB:
P26255
UniParc:
UPI0000126706
EMBL:
S73473,
S56152,
S56481,
M74716
Ensembl:
ENSRNOG00000012674
KO:
rno:25645
|
| Nucleutide sequences |
EMBL-CDS:
AAB20702.1,
AAA74470.1,
AAB25520.1,
AAB25521.1
Ensembl_TRS:
ENSRNOT00000016907
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000016907
RefSeq:
XP_008769537.1,
NP_037240.2
|
| Others |
UniRef100:
UniRef100_P26255
UniRef90:
UniRef90_P25962
UniRef50:
UniRef50_P13945
UniGene:
Rn.10100
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员