| Type | Description |
|---|---|
| Definition | protein kinase cAMP-activated catalytic subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2018-06-02 10:19:00 | These results suggest that urotensin II induces cardiomyocyte hypertrophy through the cAMP-dependent protein kinase A -mediated upregulation of phospholamban phosphorylation at Ser16, which provides a new experimental foundation for the prevention and/or treatment of cardiac hypertrophy. | 28656205 |
| 2018-02-10 10:49:00 | Using pharmacological and genetic approaches combined with real-time FRET imaging and high resolution microscopy, we demonstrate that in rat cardiac myocytes and other cell types mitochondrial PDE2A2 regulates local cAMP levels and phosphorylation of Drp1. | 28463107 |
| 2018-01-27 11:16:00 | SERCA2a and the pathway are inhibited by TSH in rat cardiomyocytes | 27206677 |
| 2017-12-16 11:42:00 | inhibition and activation of dramatically affected the phosphorylation state of Ctnnb1 and Gsk3beta, which regulates the differentiation of neural stem cells. | 27097102 |
| 2017-12-02 11:02:00 | This study showed an anti-silicotic effect of db-cAMP that was mediated via signaling. Furthermore, the findings offer novel insight into the potential use of cAMP signaling for therapeutic strategies to treat silicosis. | 28222740 |
| Type | IDs |
|---|---|
| Synonymous | Cs-PKA, PKCA1 |
| Gene |
UniProtKB-ID:
A1L1M0_RAT
UniprotKB:
A1L1M0
UniParc:
UPI00002502F0
EMBL:
AABR07043167,
BC129128,
CH473972
Ensembl:
ENSRNOG00000005257
KO:
rno:25636
|
| Nucleutide sequences |
EMBL-CDS:
AAI29129.1,
EDL92251.1
Gene_ORFName:
rCG_51506
Ensembl_TRS:
ENSRNOT00000041717
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000044732
RefSeq:
NP_001094392.1,
XP_017456673.1,
XP_006255281.1
|
| Others |
UniRef100:
UniRef100_A1L1M0
UniRef90:
UniRef90_P05132
UniRef50:
UniRef50_P05132
UniGene:
Rn.20
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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