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25635 Mc4r

25635

Mc4r

melanocortin 4 receptor

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition melanocortin 4 receptor

研究结论

Date Results Publications
2020-05-23 10:07:00 The increase in hypothalamic nesfatin-1 participates in regulating feeding behavior through the MC3/4R-ERK signaling especially after SG and RYGB. 31260713
2020-04-25 13:02:00 deficiency was associated with impaired ventilatory responses to hypercapnia independently of obesity 30466186
2019-10-19 10:36:00 findings suggest that alpha-MSH suppresses I A by activating MC4R, which is coupled sequentially to the Gbetagamma complex of the Gi/o-protein and downstream class I PI3K-dependent p38alpha signaling, thereby increasing TG neuronal excitability and mechanical pain sensitivity in rats. 30745360
2018-06-30 11:22:00 MC3R deficiency caused a reduction of food intake and body weight, whereas at the same time exhibited additive effects on top of MC4R deficiency on lipid and glucose metabolism. 27713523
2018-05-19 11:09:00 Thus study demonstrated that Adolescent Alcohol Exposure-Induced Changes in melanocortin 4 receptor. 28575455

名称对应

Type IDs
Gene
UniProtKB-ID: MC4R_RAT
UniprotKB: P70596
UniParc: UPI000012ED4F
EMBL: U67863
Ensembl: ENSRNOG00000018692
KO: rno:25635
Nucleutide sequences
EMBL-CDS: AAB36517.1
Ensembl_TRS: ENSRNOT00000025223
Protein sequencees
Ensembl_PRO: ENSRNOP00000025223
RefSeq: NP_037231.1
Others
UniRef100: UniRef100_P70596
UniRef90: UniRef90_P32245
UniRef50: UniRef50_P32245
UniGene: Rn.10620

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