| Type | Description |
|---|---|
| Definition | pyruvate kinase M1/2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:20:00 | Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via Signaling. | 32503893 |
| 2021-03-13 13:15:00 | PKM2 regulates angiogenesis of VR-EPCs through modulating glycolysis, mitochondrial fission, and fusion. | 32017072 |
| 2021-01-23 13:03:00 | Pyruvate Kinase M2 Mediates Glycolysis in the Lymphatic Endothelial Cells and Promotes the Progression of Lymphatic Malformations. | 33130045 |
| 2019-12-14 12:01:00 | Study found that the Warburg effect was increased in liver precancerous lesions in rats. Pkm2 and phosphorylated Stat3 were upregulated in activated oval cells in liver precancerous lesions. Stat3 activation promoted the clonal formation rate, aneuploidy, alpha-fetoprotein expression, PCNA expression, G1/S phase transition, the Warburg effect, Pkm2 phosphorylation, and nuclear translocation in transformed WB-F344 cells. | 31086462 |
| 2019-11-30 10:16:00 | SIRT1 may regulate acetylation level of NSE and PKM through deacetylation and further regulate their catalytic activity. | 31202897 |
| Type | IDs |
|---|---|
| Synonymous | PK, PKM12, Pk3, Pkm2 |
| Gene |
UniProtKB-ID:
KPYM_RAT
UniprotKB:
P11980
UniParc:
UPI0000047299,
UPI0000047298
EMBL:
X15800,
M14377,
M24359
Ensembl:
ENSRNOG00000011329
KO:
rno:25630
|
| Nucleutide sequences |
EMBL-CDS:
CAA33799.1,
AAB93666.1,
AAB93667.1
Ensembl_TRS:
ENSRNOT00000015332
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000015331
RefSeq:
XP_006243250.2,
NP_445749.1,
XP_006243252.1,
XP_017450969.1
|
| Others |
UniRef100:
UniRef100_P11980
UniRef90:
UniRef90_P52480
UniRef50:
UniRef50_P30613
UniGene:
Rn.1556
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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