| Type | Description |
|---|---|
| Definition | pancreas associated transcription factor 1a |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:28:00 | Clinical Characteristics and Long-term Follow-up of Patients with Diabetes Due To PTF1A Enhancer Mutations. | 32893856 |
| 2018-12-29 10:16:00 | non-neural progenitor transcription factor Ptf1a alone is sufficient to directly reprogram mouse and human fibroblasts into self-renewable induced neural stem cells capable of differentiating into functional neurons, astrocytes and oligodendrocytes, and improving cognitive dysfunction of Alzheimer's disease mouse models when transplanted | 30030434 |
| 2017-06-24 12:00:00 | Study describes the wide range of gene control by PTF1A that maintains the specific characteristics of pancreatic acinar cell identity and differentiation. PTF1A controls the pancreatic acinar transcription program by direct action at a thousand genes and in collaboration with other less cell type-restricted factors to ensure acinar cell homeostasis and to suppress other cell-type-specific programs. | 27697859 |
| 2017-06-10 11:40:00 | Data show isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation | 27284104 |
| 2016-08-20 10:04:00 | The results of this study suggested Ptf1a-dependent cell-fate misspecification as a novel mechanism of human brainstem pathology. | 26937009 |
| Type | IDs |
|---|---|
| Synonymous | PACA, PAGEN2, PTF1-p48, bHLHa29, p48 |
| Gene |
UniProtKB-ID:
PTF1A_HUMAN
UniprotKB:
Q7RTS3
UniParc:
UPI000018F612
EMBL:
AL139281,
BK000272,
AF181999
Ensembl:
ENSG00000168267
KO:
hsa:256297
|
| Nucleutide sequences |
EMBL-CDS:
AAG09441.1,
DAA01052.1
Ensembl_TRS:
ENST00000376504
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000365687
RefSeq:
NP_835455.1
|
| Others |
UniRef100:
UniRef100_Q7RTS3
UniRef90:
UniRef90_Q7RTS3
UniRef50:
UniRef50_Q9QX98
UniGene:
Hs.351503
CCDS:
CCDS7143.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员