| Type | Description |
|---|---|
| Definition | chymase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:22:00 | Chymase activity in synovial fluids of collagen-induced-arthritis rats regulates gelatinase release and promotes synovial fibroblasts proliferation via FAK/p21 signaling pathway. | 31036322 |
| 2018-07-07 10:49:00 | The pathobiologic response in WKY rats was directly linked to increases in cardiac gene expression and enzymatic activity of chymase and modest reductions in ACE2 activity. | 28748720 |
| 2017-05-27 12:16:00 | Compared to chymase, ACE-mediated angiotensin-(1-12) metabolism in the heart was several fold lower. Overall our findings suggest that angiotensin-(1-12), not Ang I, is the better substrate for Ang II formation by chymase in adult rats. | 27465904 |
| 2016-12-17 10:39:00 | In a pure VO model, chymase produced in adult cardiac fibroblasts leads to autophagic degradation of newly synthesized intracellular procollagen I, suggesting a new role of chymase in extracellular matrix degradation. | 26807691 |
| 2012-11-03 11:10:00 | The results indicate an important role for chymase in inducing fibrosis through TGF-beta1 activation, parallel with Ang II effects. | 22875344 |
| Type | IDs |
|---|---|
| Synonymous | MCP3P, Mcpt5 |
| Gene |
UniProtKB-ID:
CMA1_RAT
UniprotKB:
P50339
UniParc:
UPI000012EDF6
EMBL:
D38495,
U67908
Ensembl:
ENSRNOG00000020563
KO:
rno:25627
|
| Nucleutide sequences |
EMBL-CDS:
AAB48261.1,
BAA07507.1
Ensembl_TRS:
ENSRNOT00000067539
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000061330
RefSeq:
NP_037224.1
|
| Others |
UniRef100:
UniRef100_P50339
UniRef90:
UniRef90_P50339
UniRef50:
UniRef50_P50339
UniGene:
Rn.10182
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员