| Type | Description |
|---|---|
| Definition | keratin 8 |
| Date | Results | Publications |
|---|---|---|
| 2012-12-08 10:59:00 | Results indicate a keratins K8/K18 intermediate filament (IF) contribution to the cell stiffness-extracellular matrix (ECM) interplay through a modulation of Rho-dependent actin organization. | 22685604 |
| 2010-01-21 00:00:00 | data imply that CK8/18 overexpression, those cytokeratins complex formation associated w/ histone type 2 H2aa3 upregulation & intermediate filament reorganization may drive neoplastic transformation of GST-P positive foci during rat hepatocarcinogenesis | 19409407 |
| 2010-01-21 00:00:00 | shear stress mediates the phosphorylation of serine residues in K8, leading to the disassembly of intermediate filaments in alveolar epithelial cells | 15972820 |
| 2010-01-21 00:00:00 | K8 is a physiological substrate for and the phosphorylation at Ser8 and Ser23 transduces, at least in part, signaling in pituitary cells | 17553064 |
| 2010-01-21 00:00:00 | cytokeratins 8 and 19 are expressed in adult striated muscle, where they may contribute to the organization of both the myoplasm and sarcolemma | 15247274 |
| Type | IDs |
|---|---|
| Synonymous | CYKER, Krt2-8 |
| Gene |
UniProtKB-ID:
K2C8_RAT
UniprotKB:
Q10758
UniParc:
UPI0000170901
EMBL:
M63482,
BC091106,
AY464139,
BC097497,
S76054
Ensembl:
ENSRNOG00000009779
KO:
rno:25626
|
| Nucleutide sequences |
EMBL-CDS:
AAH97497.1,
AAH91106.1,
AAA19668.1,
AAA19667.1,
AAR36875.1
Ensembl_TRS:
ENSRNOT00000038480
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000029068
RefSeq:
NP_955402.1
|
| Others |
UniRef100:
UniRef100_Q10758
UniRef90:
UniRef90_P05787
UniRef50:
UniRef50_P05787
UniGene:
Rn.11083
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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