| Type | Description |
|---|---|
| Definition | poly(A) specific ribonuclease subunit PAN3 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 12:59:00 | the present study revealed that circPAN3 is most likely a key modulator for acquired drug resistance of AML, which may facilitate drug resistance in AML cells by regulating autophagy as an autophagy inducer via the AMPK/mTOR pathway. | 31401408 |
| 2017-10-14 10:59:00 | These results reveal a new fundamental step governing mammalian mRNA metabolism. We propose that the first phase of deadenylation, coordinated through the interplay among the two Pan3 isoforms, Pan2, and PABP, represents a cytoplasmic mRNA maturation step important for proper mRNA turnover. | 28559491 |
| 2015-02-14 13:15:00 | arsenite-induced oxidative stress inhibits deadenylation of mRNA primarily through downregulation of Tob and Pan3, both of which mediate the recruitment of deadenylases to mRNA | 25446091 |
| 2010-01-21 00:00:00 | hPan2 and hPan3 have roles in mRNA decay and exhibit cytoplasmic co-localization | 14583602 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
PAN3_HUMAN
UniprotKB:
Q58A45
UniParc:
UPI0000F3BE46,
UPI0001914BA3,
UPI0001BE8111,
UPI0001BE8112
EMBL:
BC024318,
BC128180,
BX647740,
AB109552,
AK091307,
BC128179,
AK296435,
EF088216,
AB107584,
AL138712,
AL356915
Ensembl:
ENSG00000152520
KO:
hsa:255967
|
| Nucleutide sequences |
EMBL-CDS:
AAH24318.1,
ABK41888.1,
AAI28180.1,
BAD93184.1,
BAC03632.1,
CAI45987.2,
BAD02262.1,
AAI28181.1,
BAH12353.1
Ensembl_TRS:
ENST00000380958
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370345
RefSeq:
XP_016876018.1,
XP_016876022.1,
NP_787050.6,
XP_011533334.1,
XP_005266390.1,
XP_016876020.1,
XP_005266389.1,
XP_016876019.1,
XP_005266391.1,
XP_011533336.1,
XP_016876017.1,
XP_016876021.1,
XP_011533335.1
|
| Others |
UniRef100:
UniRef100_Q58A45
UniRef90:
UniRef90_Q58A45
UniRef50:
UniRef50_Q58A45
UniGene:
Hs.645015
CCDS:
CCDS9329.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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