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25579 Map3k12

25579

Map3k12

mitogen activated protein kinase kinase kinase 12

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition mitogen activated protein kinase kinase kinase 12

研究结论

Date Results Publications
2021-02-20 13:29:00 The Map3k12 (Dlk)/JNK3 signaling pathway is required for pancreatic beta-cell proliferation during postnatal development. 32189007
2016-06-28 10:16:00 These findings explain how DLK specifically mediates nerve injury responses and reveal a novel cellular mechanism that ensures the specificity of neuronal kinase signaling. 26719418
2013-05-04 12:33:00 DLK is required for RGC JNK activation and cell death in a rodent model of optic neuropathy 23431148
2010-01-21 00:00:00 Dlk is expressed in a subpopulation of oval cells and that Dlk(+) cells represent intermediate cells between Dlk(-) oval cells and mature hepatocytes. 15567716
2010-01-21 00:00:00 MUK/DLK/ZPK, and JNK activity increase potently and temporally in newly generated neurons in developing mouse telencephalon during radial migration 12223406

名称对应

Type IDs
Synonymous DLK, MUK, PK, Zpk
Gene
UniProtKB-ID: M3K12_RAT, F1LQ89_RAT
UniprotKB: Q63796, F1LQ89
UniParc: UPI000012EADB, UPI0002AB8C51
EMBL: D49785, AC109743
Ensembl: ENSRNOG00000015134
KO: rno:25579
Nucleutide sequences
EMBL-CDS: BAA08621.1
Ensembl_TRS: ENSRNOT00000020437
Protein sequencees
Ensembl_PRO: ENSRNOP00000020437
RefSeq: XP_006242444.1, NP_037187.1, XP_006242443.1
Others
UniRef100: UniRef100_F1LQ89, UniRef100_Q63796
UniRef90: UniRef90_Q60700
UniRef50: UniRef50_Q60700
UniGene: Rn.146082

全选

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研究热度

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