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255743 NPNT

255743

NPNT

nephronectin

protein-coding

Homo sapiens

基因描述

Type Description
Definition nephronectin

研究结论

Date Results Publications
2019-11-09 10:50:00 Serum Npnt was found to be higher in silicosis patients compared to healthy volunteers and seems to play a role in the progression of fibrosis with other cytokines. [review] 31130697
2018-05-26 12:09:00 Biopsies from patients with focal segmental glomerulosclerosis and membranous nephropathy had increased miR-378a-3p expression and reduced glomerular levels of NPNT. 28476557
2018-04-28 10:43:00 Nephronectin (NPNT), a member of the epidermal growth factor (EGF) repeat superfamily proteins and a homologue of EGFL6, is expressed in osteoblasts. Intriguingly, the gene expression of NPNT is reduced in the bone of osteoporosis patients. 27782206
2014-02-08 11:06:00 The expression of nephronectin was sufficient to discriminate DN from other kidney diseases with mesangial matrix expansion and nodular lesions. 23689482
2012-12-08 10:07:00 Nephronectin is associated with the development of diabetic glomerulosclerosis. 22172726

名称对应

Type IDs
Synonymous EGFL6L, POEM
Gene
UniProtKB-ID: NPNT_HUMAN
UniprotKB: Q6UXI9
UniParc: UPI00001612DF, UPI0001AE7511, UPI000049DFE8, UPI0001AE7510, UPI00001A5D06, UPI0001AE758D
EMBL: AK302477, CH471057, AC093782, AK295772, AK304721, AK304279, AY358336, AC109361, AK290029
Ensembl: ENSG00000168743
KO: hsa:255743
Nucleutide sequences
EMBL-CDS: BAG63765.1, BAF82718.1, BAG65484.1, EAX06196.1, BAG65139.1, BAG58596.1, AAQ88702.1
Gene_ORFName: UNQ295/PRO334
Ensembl_TRS: ENST00000379987, ENST00000506666, ENST00000305572, ENST00000514622, ENST00000427316, ENST00000453617
Protein sequencees
Ensembl_PRO: ENSP00000422044, ENSP00000389252, ENSP00000402884, ENSP00000369323, ENSP00000302557, ENSP00000422474
RefSeq: XP_011530125.1, NP_001171620.1, XP_011530124.1, XP_016863473.1, XP_011530127.1, XP_011530126.1, NP_001171619.1, XP_005262945.1, NP_001028219.1, XP_011530122.1, NP_001171621.1, NP_001171622.1
Others
UniRef100: UniRef100_Q6UXI9
UniRef90: UniRef90_Q6UXI9
UniRef50: UniRef50_Q91V88-3
UniGene: Hs.518921
CCDS: CCDS54784.1, CCDS54787.1, CCDS54786.1, CCDS34046.1, CCDS54785.1

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