| Type | Description |
|---|---|
| Definition | syntaxin binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:15:00 | Munc13 activates the Munc18-1/syntaxin-1 complex and enables Munc18-1 to prime SNARE assembly. | 32643828 |
| 2021-01-23 13:02:00 | Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly. | 32669573 |
| 2019-02-23 13:15:00 | Study data suggest that Munc18-1 and Munc13-1 together serve as a functional template to orchestrate SNARE complex assembly. | 30622273 |
| 2018-02-24 11:14:00 | Together with previous studies, these data support a model whereby Munc18-1 acts as a template for SNARE complex assembly, and autoinhibition of synaptobrevin binding contributes to enabling regulation of neurotransmitter release by Munc13-1. | 28477408 |
| 2017-10-07 10:05:00 | Munc18a promotes membrane clustering in a step that is independent of trans-SNARE activation. | 28827281 |
| Type | IDs |
|---|---|
| Synonymous | ANC18HA, Munc18-1, NSEC1A, Sec1, Unc18-1, n-sec1, nSec1, rbSec1, rbSec1A, rbSec1B |
| Gene |
UniProtKB-ID:
STXB1_RAT
UniprotKB:
P61765
UniParc:
UPI0000006C0B,
UPI0000000ED9
EMBL:
U21116,
U06069,
BC088850,
L26087,
L26264
Ensembl:
ENSRNOG00000015420
KO:
rno:25558
|
| Nucleutide sequences |
EMBL-CDS:
AAA17987.1,
AAA19246.1,
AAB41113.1,
AAH88850.1,
AAA96350.1
Ensembl_TRS:
ENSRNOT00000021178,
ENSRNOT00000021189
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000021178,
ENSRNOP00000021189
RefSeq:
NP_037170.1,
XP_006234001.1
|
| Others |
UniRef100:
UniRef100_P61764
UniRef90:
UniRef90_P61764
UniRef50:
UniRef50_P61764
UniGene:
Rn.80843
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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