| Type | Description |
|---|---|
| Definition | gamma-aminobutyric acid type A receptor alpha2 subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:27:00 | Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse. | 33140451 |
| 2020-10-03 12:58:00 | FRMD7 Mutations Disrupt the Interaction with GABRA2 and May Result in Infantile Nystagmus Syndrome. | 32446246 |
| 2020-06-20 12:24:00 | The strongest association for alcohol use disorder (rs3756007) was located in GABRA2, the strongest association for antisocial behavior (rs11941860) was located in GABRG1, and the interaction term yielded top associations in GABRA2 (rs2119183) and the intergenic region between GABRA2 and GABRG1 (rs536599). | 31790348 |
| 2019-07-20 11:38:00 | The GABRA2 p.T292K variant reduced channel expression and produced mutant channels that were tonically open, even in the absence of GABA. | 29961870 |
| 2019-04-13 11:37:00 | To test an age-varying interaction between a single nucleotide polymorphism in the GABRA2 gene (rs279845) and a preventive intervention in predicting alcohol misuse in a longitudinal study of adolescents (ages 11-20). Intervention effects on adolescent alcohol misuse may differ by genotype, and evidence suggests that the interaction between GABRA2 and intervention effects on alcohol use may vary with age. | 28185103 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GBRA2_HUMAN,
E9PBQ7_HUMAN,
A0A024R9X6_HUMAN
UniprotKB:
P47869,
E9PBQ7,
A0A024R9X6
UniParc:
UPI000049193F,
UPI000013DC88,
UPI0001914A97
EMBL:
AK125179,
AC093745,
AK293466,
AC084352,
AK289662,
AC104072,
S62907,
AB209295,
CH471069,
AC095060
Ensembl:
ENSG00000151834
KO:
hsa:2555
|
| Nucleutide sequences |
EMBL-CDS:
AAB27278.1,
BAH11514.1,
BAG54159.1,
BAD92532.1,
BAF82351.1,
EAW93022.1,
EAW93025.1,
EAW93024.1
Gene_ORFName:
hCG_15318
Ensembl_TRS:
ENST00000510861,
ENST00000356504,
ENST00000514090,
ENST00000381620,
ENST00000507069
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348897,
ENSP00000421828,
ENSP00000371033,
ENSP00000421300,
ENSP00000427603
RefSeq:
XP_011511977.1,
XP_024309735.1,
NP_001364082.1,
NP_001107647.1,
NP_001364074.1,
NP_001364073.1,
NP_001364081.1,
XP_024309734.1,
NP_001364083.1,
NP_001317619.1,
XP_024309732.1,
NP_001364084.1,
NP_001273756.1,
NP_000798.2,
NP_001364080.1,
NP_001364075.1,
NP_001364076.1,
NP_001364077.1,
NP_001364078.1,
NP_001364079.1
|
| Others |
UniRef100:
UniRef100_P47869,
UniRef100_E9PBQ7
UniRef90:
UniRef90_P47869,
UniRef90_A0A337SQD9
UniRef50:
UniRef50_P47869
UniGene:
Hs.116250
CCDS:
CCDS3471.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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