Type | Description |
---|---|
Definition | GA binding protein transcription factor subunit beta 1 |
Date | Results | Publications |
---|---|---|
2020-10-31 13:13:00 | LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells. | 31700067 |
2019-11-09 11:06:00 | G allele of (rs7181866 A/G) was found to be significantly associated with risk for obesity among T2DM subjects | 30904536 |
2019-06-29 11:16:00 | Study in glioblastoma cells shows that genetic disruption of GABPbeta1L (beta1L), a tetramer-forming isoform of GABP that is dispensable for normal development, results in TERT silencing in a TERT promoter mutation-dependent manner. Reducing TERT expression by disrupting beta1L culminates in telomere loss and cell death exclusively in TERT promoter mutant cells. | 30205050 |
2018-10-27 11:20:00 | Data revealed high expression of GABPB1 in clear cell renal cell carcinoma (ccRCC) tissues and cell lines. Its knockdown significantly decreased the colony formation ability via induction of p21Waf/Cip1 expression. Furthermore, the patients at high risk of a poor survival outcome exhibited the highest expression level of GABPB1. These findings imply that GABPB1 serves an important role in the progression of ccRCC. | 29845229 |
2017-11-04 11:58:00 | Ectopic overexpression of a dominant-negative acting GABP mutant led to impaired myeloid differentiation of CD34(+) hematopoietic stem/progenitor cells. | 27100840 |
Type | IDs |
---|---|
Synonymous | BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB-1, GABPB2, NRF2B1, NRF2B2 |
Gene |
UniProtKB-ID:
GABP1_HUMAN,
A0A024R5X6_HUMAN,
A0A024R5R5_HUMAN
UniprotKB:
Q06547,
A0A024R5X6,
A0A024R5R5
UniParc:
UPI000012AFB3,
UPI000002AA2D,
UPI000002AA2C,
UPI000012AFB4
EMBL:
BC036080,
U13047,
BC050702,
D13316,
U13045,
U13048,
U13046,
D13317,
BT006652,
BC016910,
CH471082,
EU159454
Ensembl:
ENSG00000104064
KO:
hsa:2553
|
Nucleutide sequences |
EMBL-CDS:
AAP35298.1,
BAA02573.1,
EAW77395.1,
AAH16910.1,
AAH50702.1,
AAA65708.1,
AAH36080.1,
ABV90874.1,
AAA65710.1,
BAA02574.1,
AAA65709.1,
AAA65707.1,
EAW77388.1,
EAW77394.1,
EAW77389.1,
EAW77392.1
Gene_ORFName:
hCG_2002404,
hCG_2002404
Ensembl_TRS:
ENST00000396464,
ENST00000380877,
ENST00000220429,
ENST00000429662,
ENST00000359031
|
Protein sequencees |
Ensembl_PRO:
ENSP00000395771,
ENSP00000220429,
ENSP00000370259,
ENSP00000351923,
ENSP00000379728
RefSeq:
XP_024305654.1,
NP_001307839.1,
NP_852092.1,
XP_024305656.1,
XP_024305652.1,
NP_002032.2,
XP_024305653.1,
XP_011519728.1,
XP_016877543.1,
NP_001307844.1,
NP_057738.1,
XP_024305651.1,
XP_024305655.1,
NP_005245.2,
XP_016877542.1,
XP_005254331.1,
NP_057739.1
|
Others |
UniRef100:
UniRef100_Q1RMI3,
UniRef100_Q06547,
UniRef100_A0A024R5R5
UniRef90:
UniRef90_Q00420-2,
UniRef90_Q06547
UniRef50:
UniRef50_Q00420-2,
UniRef50_Q06547
UniGene:
Hs.654350
CCDS:
CCDS45258.1,
CCDS10136.1,
CCDS32239.1,
CCDS10135.1
|
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Refseq |
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