| Type | Description |
|---|---|
| Definition | GA binding protein transcription factor subunit alpha |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:05:00 | TERT promoter mutations and GABP transcription factors in carcinogenesis: More foes than friends. | 32768523 |
| 2019-06-22 12:45:00 | Therefore, we proposed that GABPA cooperates with the states of histone acetylation to act as a novel bookmarking factor which, may negatively regulate transcription during the early G1 phase. | 30836589 |
| 2019-03-02 11:04:00 | a positive correlation between GABPA and DICER1 expression was seen in multiple types of malignancies. Taken together, despite its stimulatory effect on the mutant TERT promoter and telomerase activation, GABPA may itself act as a tumor suppressor rather than an oncogenic factor to inhibit invasion/metastasis in thyroid carcinomas. | 30181547 |
| 2018-12-29 11:33:00 | enhanced ETS factor activity and the transcription of ETS family target genes related to spliceosome function and cell death induction via alternate MCL1 splicing, is reported. | 29118074 |
| 2018-05-12 12:02:00 | Data indicate the essential role of the GABP transcription factor in activating translocase of inner mitochondrial membrane 23 TIMM23 and TIMM23B expression. | 29413900 |
| Type | IDs |
|---|---|
| Synonymous | E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07 |
| Gene |
UniProtKB-ID:
GABPA_HUMAN,
Q8IYS3_HUMAN,
A8IE48_HUMAN
UniprotKB:
Q06546,
Q8IYS3,
A8IE48
UniParc:
UPI00000741FA,
UPI000012AFB2
EMBL:
BC035031,
JQ313900,
EU627790,
EU159453,
D13318,
CH471079,
U13044
Ensembl:
ENSG00000154727
KO:
hsa:2551
|
| Nucleutide sequences |
EMBL-CDS:
BAA02575.1,
AAA65706.1,
AAH35031.1,
EAX09968.1,
ABV90873.1,
EAX09967.1,
AFH41795.1,
ACD11490.1,
EAX09969.1
Gene_ORFName:
hCG_401151
Ensembl_TRS:
ENST00000400075,
ENST00000354828
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000346886,
ENSP00000382948
RefSeq:
XP_011527823.1,
NP_002031.2,
XP_011527822.1,
NP_001184226.1,
XP_016883802.1,
XP_005260995.1,
XP_024307830.1
|
| Others |
UniRef100:
UniRef100_Q06546,
UniRef100_Q8IYS3
UniRef90:
UniRef90_Q06546
UniRef50:
UniRef50_Q06546
UniGene:
Hs.473470
CCDS:
CCDS13575.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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