| Type | Description |
|---|---|
| Definition | GRB2 associated binding protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:14:00 | Increased expression of GAB1 promotes inflammation and fibrosis in systemic sclerosis. | 31505074 |
| 2020-07-18 10:53:00 | Gab1 enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner | 31651330 |
| 2020-02-29 12:08:00 | Gab1 expression in Ewing sarcoma, rhabdomyosarcoma and synovial sarcoma may have prognostic significance | 31443923 |
| 2020-01-18 11:19:00 | Results identified GAB1 as a direct target of miR-590 in non-small cell lung cancer (NSCLC). Its knockdown had the same effect as overexpression of miR-590 in NSCLC. Moreover, its overexpression partially reversed the suppressive effect of miR-590 on NSCLC. | 30280777 |
| 2019-09-14 11:45:00 | Modifier variant of METTL13 suppresses human GAB1-associated profound deafness. | 29408807 |
| Type | IDs |
|---|---|
| Synonymous | DFNB26 |
| Gene |
UniProtKB-ID:
GAB1_HUMAN,
Q9HA84_HUMAN
UniprotKB:
Q13480,
Q9HA84
UniParc:
UPI000013D37B,
UPI0000232A33,
UPI000006D52A
EMBL:
AC097658,
AC104685,
AK022142,
CH471056,
DQ021880,
BC064848,
AK289767,
U43885
Ensembl:
ENSG00000109458
KO:
hsa:2549
|
| Nucleutide sequences |
EMBL-CDS:
EAX05072.1,
AAY26398.1,
AAC50380.1,
BAF82456.1,
AAY40964.1,
AAH64848.1,
BAB13970.1
Ensembl_TRS:
ENST00000262995,
ENST00000262994
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000262995,
ENSP00000262994
RefSeq:
NP_002030.2,
NP_997006.1,
XP_016863455.1,
XP_006714231.1,
XP_016863459.1,
XP_016863456.1,
XP_016863458.1,
XP_006714230.1,
XP_016863457.1,
XP_016863460.1
|
| Others |
UniRef100:
UniRef100_Q13480,
UniRef100_Q9HA84
UniRef90:
UniRef90_Q13480,
UniRef90_Q9HA84
UniRef50:
UniRef50_A0A452IHW2,
UniRef50_Q13480
UniGene:
Hs.80720,
Hs.618456
CCDS:
CCDS3759.1,
CCDS3760.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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