| Type | Description |
|---|---|
| Definition | potassium voltage-gated channel subfamily J member 8 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-16 10:52:00 | it can be concluded that mitoKATP channels regulate mitochondrial dynamics to participate in rotenone-induced Parkinson's disease mainly attributes to the pore subunits of Kir6.1. | 29353068 |
| 2017-11-04 10:45:00 | In vascular smooth muscle KATP channel subunits Kir6.1 and SUR2B contribute to modify the functionality of this channel in hypertension with age. | 27035370 |
| 2017-10-28 10:49:00 | both Kir6.1(V65M) and Kir6.2(V64M) mutations essentially abolish high-affinity sensitivity to the KATP blocker glibenclamide in both intact cells and excised patches. This raises the possibility that, at least for some CS mutations, sulfonylurea therapy may not prove to be successful and highlights the need for detailed pharmacogenomic analyses of CS mutations. | 28842488 |
| 2016-06-28 11:17:00 | Our results suggest that pretreatment with 0.5 MAC sevoflurane is as effective as IPC against intestinal ischemia-reperfusion injury. The activation of and mKATP may be involved in the protective mechanisms of SPC. | 26505750 |
| 2015-05-16 10:33:00 | Suggest that the increase in KATP channel subunits, SUR2 and Kir6.1, in the rostral ventrolateral medulla may be responsible for the greater sympathetic outflow and pressor effect of hydroxylamine in Ad-cystathionine beta-synthetase injected rats. | 25599573 |
| Type | IDs |
|---|---|
| Synonymous | Kir6.1, UKATP1, uKATP-1 |
| Gene |
UniProtKB-ID:
KCNJ8_RAT
UniprotKB:
Q63664
UniParc:
UPI000002E77A
EMBL:
AB043637,
AB043636,
D42145
Ensembl:
ENSRNOG00000013463
KO:
rno:25472
|
| Nucleutide sequences |
EMBL-CDS:
BAA96238.1,
BAA96237.1,
BAA07716.1
Ensembl_TRS:
ENSRNOT00000018057
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000018057
RefSeq:
NP_058795.3
|
| Others |
UniRef100:
UniRef100_Q63664
UniRef90:
UniRef90_Q15842
UniRef50:
UniRef50_Q15842
UniGene:
Rn.229203
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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