| Type | Description |
|---|---|
| Definition | meiosis specific with OB-fold |
| Date | Results | Publications |
|---|---|---|
| 2021-01-02 12:53:00 | The ssDNA-binding protein MEIOB acts as a dosage-sensitive regulator of meiotic recombination. | 33166385 |
| 2020-07-25 11:15:00 | MEIOB is the major, and most likely also the exclusive, contributor of the testicular pathology found in the seven non-obstructive azoospermia patients across two studies. | 30838384 |
| 2019-08-24 12:34:00 | This truncating MEIOB variant is expected to provoke meiotic defects and a depleted follicular stock, as in Meiob(-/-) mice. This is the first molecular defect reported in a meiosis-specific single-stranded DNA-binding protein (SSB) responsible for POI. | 31000419 |
| 2016-09-19 08:29:00 | MEIOB interacts with RPA and | 24240703 |
| 2014-03-22 11:05:00 | we propose that RPA and this new single-strand DNA binding protein MEIOB, are essential to ensure the proper stabilization of recombinases which is required for successful homology search and meiotic recombination. | 24068956 |
| Type | IDs |
|---|---|
| Synonymous | C16orf73, SPGF22, gs129 |
| Gene |
UniProtKB-ID:
MEIOB_HUMAN
UniprotKB:
Q8N635
UniParc:
UPI000059D2EB,
UPI000198C771
EMBL:
BC029829,
AL031722,
AE006639,
AL499628,
AL132823
Ensembl:
ENSG00000162039
KO:
hsa:254528
|
| Nucleutide sequences |
EMBL-CDS:
AAK61296.1,
CAM26474.1,
AAH29829.1,
CAM28376.1
Ensembl_TRS:
ENST00000397344,
ENST00000325962
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000314484,
ENSP00000380504
RefSeq:
NP_689977.2,
NP_001157032.1
|
| Others |
UniRef100:
UniRef100_Q8N635
UniRef90:
UniRef90_Q8N635
UniRef50:
UniRef50_Q8N635
UniGene:
Hs.729604
CCDS:
CCDS53983.1,
CCDS10449.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员