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25451 Gabrb2

25451

Gabrb2

gamma-aminobutyric acid type A receptor beta 2 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition gamma-aminobutyric acid type A receptor beta 2 subunit

研究结论

Date Results Publications
2019-08-03 10:07:00 In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... 29706582
2017-05-13 13:43:00 the subunit arrangement of alpha4beta2delta GABAA receptors is not strongly predefined but is mostly satisfying the 2:2:1 subunit stoichiometry for alpha4, beta2, and delta subunits and that several subunit arrangements result in receptors with similar functional properties tuned to physiological conditions. 27382064
2015-06-20 11:15:00 The data of this study reveal that GABAA receptor beta2 and beta3 decrease following 1 h of acute restraint stress and may play a critical role in stress-induced hyperalgesia. 24992900
2013-11-16 11:13:00 These studies identify a novel gephyrin-binding motif in GABA(A) R beta2 and beta3 large cytoplasmic loops. 23205938
2012-07-14 10:37:00 The interaction between midazolam and propofol is affected by receptor subtype, and protein kinase phosphorylation influences their interaction on the alpha(1)beta(2)gamma(2)L receptor. 21474657

名称对应

Type IDs
Synonymous GARB2
Gene
UniProtKB-ID: GBRB2_RAT
UniprotKB: P63138
UniParc: UPI00000041E5
EMBL: AY574251, X15467
Ensembl: ENSRNOG00000003680
KO: rno:25451
Nucleutide sequences
EMBL-CDS: AAS90347.1, CAA33494.1
Ensembl_TRS: ENSRNOT00000004970
Protein sequencees
Ensembl_PRO: ENSRNOP00000004970
RefSeq: XP_006246189.1, NP_037089.1, XP_008765857.1
Others
UniRef100: UniRef100_P63138
UniRef90: UniRef90_P63138
UniRef50: UniRef50_P63138
UniGene: Rn.207158

全选

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研究热度

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