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25450 Gabrb1

25450

Gabrb1

gamma-aminobutyric acid type A receptor beta 1 subunit

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition gamma-aminobutyric acid type A receptor beta 1 subunit

研究结论

Date Results Publications
2019-08-03 10:07:00 In inhibitory transmission onto hippocampal CA1 pyramidal cells, deletion of all beta subunits 1, 2, and 3 completely eliminated inhibitory responses. In addition, only knockout of beta3, alone or in combination with another beta subunit, impaired inhibitory synaptic transmission. expression of beta3 alone on the background of the beta1-3 subunit knockout was sufficient to restore synaptic and extrasynaptic inhibitory ... 29706582
2013-11-16 11:20:00 we conclude that is a greater contribution of beta(1) -subunit-containing GABA(A) receptors following oxygen and glucose deprivation in cerebellar Purkinje cells 23176253
2013-04-13 10:36:00 Bone marrow stem cells and adult stem cells were found to express GABA-A alpha2 and beta3, but not beta1 mRNA transcripts. 22215379
2012-06-23 12:12:00 The endogenous sleep pathway in the hypothalamus operates through the beta1- containing GABAAR whereas inhibition of neuronal firing (anaesthesia) by low propofol doses relies on beta3- containing GABAAR. 21735059
2012-02-11 10:31:00 Following spinal nerve ligation, activated microglia in the spinal cord modulate peripheral nerve injury-induced downregulation of GABA(B)R1a receptor expression in the spinal dorsal horn. 21242699

名称对应

Type IDs
Synonymous GARB1
Gene
UniProtKB-ID: GBRB1_RAT
UniprotKB: P15431
UniParc: UPI000012AFAD
EMBL: X15466
Ensembl: ENSRNOG00000002327
KO: rno:25450
Nucleutide sequences
EMBL-CDS: CAA33493.1
Ensembl_TRS: ENSRNOT00000003170
Protein sequencees
Ensembl_PRO: ENSRNOP00000003170
RefSeq: NP_037088.1, XP_008768358.2
Others
UniRef100: UniRef100_P15431
UniRef90: UniRef90_P15431
UniRef50: UniRef50_P15431
UniGene: Rn.207157

全选

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研究热度

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