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25439 F2r

25439

F2r

coagulation factor II (thrombin) receptor

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition coagulation factor II (thrombin) receptor

研究结论

Date Results Publications
2020-09-19 16:28:00 Protease-activated receptor 1 inhibitor improves brain edema in rats with intracerebral hemorrhage. 32726124
2020-01-11 11:44:00 FXIa mainly elicits the Ca(2+) signal via the PAR1/CaV1.2-mediated Ca(2+) influx. 30566391
2019-06-23 00:15:00 The present study demonstrated that the inhibition of protease-activated receptor 1 attenuates status epilepticus-induced alterations in neural plasticity in Shaffer collateral - CA1 hippocampal synaptic pathway. 30391321
2018-06-02 10:43:00 SCH inhibited the death of PC12 neurons from the cytotoxicity of activated BV2 cells via activation of the PI3K/Akt pathway. These neuro-protective effects appear to be related to inhibition of PAR-1, and represents a novel neuroprotective strategy that could has potential for use in therapeutic interventions of neuroinflammatory disease. 27910893
2018-05-19 10:19:00 Activated thrombin receptor PAR1 induced Src activation. 27385592

名称对应

Type IDs
Synonymous Par1, TRGPC
Gene
UniProtKB-ID: Q5U324_RAT
UniprotKB: Q5U324
UniParc: UPI0000456062
EMBL: BC085759, CH473955
KO: rno:25439
Nucleutide sequences
EMBL-CDS: AAH85759.1, EDM10103.1
Gene_ORFName: rCG_44761
Protein sequencees
RefSeq: NP_037082.2
Others
UniRef100: UniRef100_Q5U324
UniRef90: UniRef90_P30558
UniRef50: UniRef50_P25116
UniGene: Rn.2609

全选

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研究热度

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