| Type | Description |
|---|---|
| Definition | coagulation factor II (thrombin) receptor |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:28:00 | Protease-activated receptor 1 inhibitor improves brain edema in rats with intracerebral hemorrhage. | 32726124 |
| 2020-01-11 11:44:00 | FXIa mainly elicits the Ca(2+) signal via the PAR1/CaV1.2-mediated Ca(2+) influx. | 30566391 |
| 2019-06-23 00:15:00 | The present study demonstrated that the inhibition of protease-activated receptor 1 attenuates status epilepticus-induced alterations in neural plasticity in Shaffer collateral - CA1 hippocampal synaptic pathway. | 30391321 |
| 2018-06-02 10:43:00 | SCH inhibited the death of PC12 neurons from the cytotoxicity of activated BV2 cells via activation of the PI3K/Akt pathway. These neuro-protective effects appear to be related to inhibition of PAR-1, and represents a novel neuroprotective strategy that could has potential for use in therapeutic interventions of neuroinflammatory disease. | 27910893 |
| 2018-05-19 10:19:00 | Activated thrombin receptor PAR1 induced Src activation. | 27385592 |
| Type | IDs |
|---|---|
| Synonymous | Par1, TRGPC |
| Gene |
UniProtKB-ID:
Q5U324_RAT
UniprotKB:
Q5U324
UniParc:
UPI0000456062
EMBL:
BC085759,
CH473955
KO:
rno:25439
|
| Nucleutide sequences |
EMBL-CDS:
AAH85759.1,
EDM10103.1
Gene_ORFName:
rCG_44761
|
| Protein sequencees |
RefSeq:
NP_037082.2
|
| Others |
UniRef100:
UniRef100_Q5U324
UniRef90:
UniRef90_P30558
UniRef50:
UniRef50_P25116
UniGene:
Rn.2609
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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||||
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