| Type | Description |
|---|---|
| Definition | eukaryotic elongation factor-2 kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-12-12 13:22:00 | NMDA-induced nitric oxide generation and CREB activation in central nervous system is dependent on eukaryotic elongation factor 2 kinase. | 32569665 |
| 2020-04-04 11:08:00 | EEF2K/eEF2 axis under GD condition mediates the inhibition of apoptotic H9c2 cell death. | 30737648 |
| 2018-02-24 10:37:00 | HSP70 also interacted with C-terminal fragment of eEF2, which could reverse the nucleus translocation and cardiomyocyte apoptosis caused by N-terminal fragment of eEF2. HSP70 draw on advantage and avoid defect of MIR through regulating phosphorylation and nucleus translocation of eEF2 | 28205128 |
| 2018-02-03 11:56:00 | The eEF2K promotor in IUGR offspring also lost the protective histone covalent modifications associated with unmethylated CGIs. | 27317589 |
| 2017-04-29 10:51:00 | Using an eEF2K gain-of-function design in vitro as well as eEF2K-KO mice, we show that eEF2K activity regulates the excitation/inhibition balance by downregulating vesicle release at inhibitory synapses and tonic inhibition. This translates into a reduced susceptibility of eEF2K-KO mice for seizures without major behavioral alterations with the exception of impaired contextual and trace fear memory | 27005990 |
| Type | IDs |
|---|---|
| Synonymous | SMEF2K |
| Gene |
UniProtKB-ID:
EF2K_RAT
UniprotKB:
P70531
UniParc:
UPI0000129C60
EMBL:
X96426,
U93849
Ensembl:
ENSRNOG00000016448
KO:
rno:25435
|
| Nucleutide sequences |
EMBL-CDS:
AAB58272.1,
CAA65286.1
Ensembl_TRS:
ENSRNOT00000022726
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000022726
RefSeq:
NP_037079.1,
XP_006230220.1,
XP_006230218.1,
XP_006230219.1
|
| Others |
UniRef100:
UniRef100_P70531
UniRef90:
UniRef90_P70531
UniRef50:
UniRef50_O00418
UniGene:
Rn.10958
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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