| Type | Description |
|---|---|
| Definition | BRCT domain protein Rad4 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-09 10:13:00 | Results show multiple BRCT domains within TOPBP1/Rad4 achieve selective and combinatorial binding of their multiple partner proteins. | 30295604 |
| 2014-11-22 10:57:00 | Rad4 mainly functions as a scaffold protein in the Chk1, not the Cds1(CHK2 in humans), checkpoint pathway. It plays a minor role or is functionally redundant with an unknown factor in Rad3 activation. | 24663817 |
| 2013-12-14 11:26:00 | we show that the simultaneous interaction of a single Rad4(TopBP1) molecule with both Thr187 phosphorylation sites in a Crb2(53BP1) dimer is essential for establishing the DNA damage checkpoint. | 24074952 |
| 2010-01-21 00:00:00 | These data suggest that Rad4TopBP1 provides a scaffold to a large complex containing checkpoint and replication proteins thereby separately enforcing checkpoint responses to DNA damage and replication perturbations during the cell cycle. | 16723501 |
| 2010-01-21 00:00:00 | data indicate that Rad4 undergoes diverse forms of regulation that are distinct in both DNA replication and checkpoint response | 17688408 |
| Type | IDs |
|---|---|
| Synonymous | cut5, dpb11, dre3 |
| Gene |
UniProtKB-ID:
RAD4_SCHPO
UniprotKB:
P32372
UniParc:
UPI0000061AF1
EMBL:
X62676,
D16627,
CU329670
EnsemblGenome:
SPAC23C4.18c
KO:
spo:SPAC23C4.18c
|
| Nucleutide sequences |
EMBL-CDS:
CAB16889.1,
CAA44548.1,
BAA04048.1
Gene_ORFName:
SPAC23C4.18c
EnsemblGenome_TRS:
SPAC23C4.18c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPAC23C4.18c.1:pep
RefSeq:
NP_593190.1
|
| Others |
UniRef100:
UniRef100_P32372
UniRef90:
UniRef90_P32372
UniRef50:
UniRef50_P32372
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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