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25432 Drd4

25432

Drd4

dopamine receptor D4

protein-coding

Rattus norvegicus

基因描述

Type Description
Definition dopamine receptor D4

研究结论

Date Results Publications
2020-06-13 10:22:00 Theexpression level of D4 receptor was also dramatically down-regulated in the arterial endothelium of rats with streptozotocin-(STZ)-induced diabetes, and the STZ-induced impairment of acetylcholine-induced vasodilation was reversed by activation of D4 receptor. 31447121
2017-12-23 10:17:00 Data provide novel evidence that the dopamine D4 receptor does not alter incentive motivation in response to cues on simple behavioural tasks. 27275521
2017-12-16 11:38:00 Dopamine D4 receptor (D4R) antagonism in the prelimbic area (PL) decreases the expression of innate fear-behavior indicating that the activation of D4R in the PL is necessary for the expression of innate fear-behavior. 28212942
2017-06-24 10:22:00 Data indicate that the anterior cingulate cortex is critically involved in parsing the appropriate response when competing stimulus-outcome associations are activated, and that signalling via dopamine D4 receptors may play a particularly important role in gating the temporal and spatial summation of salient events. 26775821
2016-06-11 10:45:00 Regulatory role of the D(4) receptor on AT(1a) receptor expression and function in VSMCs and suggest that targeting the action of the D(4) receptor may represent an effective therapeutic approach for the treatment of cardiovascular diseases. 25832920

名称对应

Type IDs
Synonymous D4RA
Gene
UniProtKB-ID: F1LLX2_RAT
UniprotKB: F1LLX2
UniParc: UPI000157ECF0
EMBL: AC118351, CH473953
Ensembl: ENSRNOG00000017927
KO: rno:25432
Nucleutide sequences
EMBL-CDS: EDM12018.1
Gene_ORFName: rCG_47250
Ensembl_TRS: ENSRNOT00000024137
Protein sequencees
Ensembl_PRO: ENSRNOP00000024137
RefSeq: XP_006230583.1, NP_037076.2, XP_006230584.1
Others
UniRef100: UniRef100_F1LLX2
UniRef90: UniRef90_P30729
UniRef50: UniRef50_P30729
UniGene: Rn.10159

全选

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研究热度

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