| Type | Description |
|---|---|
| Definition | cytochrome P450 family 7 subfamily A member 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 12:02:00 | The increased CDCAs concentrations activated Fxr-Fgf15 pathway in ileum to result in the mRNA expression of Cyp7a1 in liver down-regulation, which inhibited cholesterol metabolizing into primary BAs to contribute to the cholesterol level increase in liver tissue in HFD-induced obesity rats. | 31288013 |
| 2019-03-02 10:52:00 | It has been demonstrated that hepatic gene expression of Cyp7a1 is directed by day/night rhythm but not daily rhythm in food intake. Combining an high-fat diet with feeding in the light/inactive period annulled CYp7a1 gene expression rhythms. | 29028359 |
| 2017-07-29 10:10:00 | lnc-HC negatively regulates cholesterol metabolism within hepatocytes through physical interaction with hnRNPA2B1. By further binding to the target messenger RNA of Cyp7a1 or Abca1, the lnc-HC-hnRNPA2B1 complex decreases expressions of the two genes that are implicated in cellular cholesterol excretion. | 26663205 |
| 2017-06-24 10:40:00 | Administration of glucocorticoids (GCs) enhanced liver bile acid uptake by increasing the expression of the major hepatocyte basolateral bile transporter (Ntcp) in rats. The reduced expression of a bile acid synthesis rate-controlling enzyme, Cyp7a1, suggests that treatment with GCs suppressed hepatic bile acid synthesis. | 27133208 |
| 2016-09-24 12:09:00 | Dietary fats and glucomannan plus spirulina added to pork significantly alters Cyp7a1 expression in Zucker rats. | 26475369 |
| Type | IDs |
|---|---|
| Synonymous | CHAP, CYP7, CYP7S1 |
| Gene |
UniProtKB-ID:
CP7A1_RAT
UniprotKB:
P18125
UniParc:
UPI0000128217
EMBL:
J05509,
U01962,
J05460,
J05430,
M59186,
J02926,
M59189,
M59188,
M59187,
M59185,
X17595,
Z14108,
M59184
Ensembl:
ENSRNOG00000009488
KO:
rno:25428
|
| Nucleutide sequences |
EMBL-CDS:
CAA78481.1,
AAA40839.1,
AAA41042.1,
AAA41041.1,
AAA03649.1,
AAA40923.1,
CAB57878.1,
AAA21144.2
Ensembl_TRS:
ENSRNOT00000012819
|
| Protein sequencees |
Ensembl_PRO:
ENSRNOP00000012819
RefSeq:
NP_037074.1
|
| Others |
UniRef100:
UniRef100_P18125
UniRef90:
UniRef90_P18125
UniRef50:
UniRef50_P18125
UniGene:
Rn.10737
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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