| Type | Description |
|---|---|
| Definition | LEM domain protein Heh1/Lem2 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-15 11:02:00 | Study propose that Schizosaccharomyces pombe Lem2 forms part of a nuclear size control mechanism, acting as a barrier to membrane flow into and out of the nuclear envelope. Lem2 deletion leads to nuclear shrinkage, accompanied by nuclear envelope blebbing, following perturbation of membrane synthesis and the ER protein Lnp1 acts as a secondary barrier, compensating for lack of Lem2. | 31015410 |
| 2018-09-29 12:05:00 | Study shows that Lem2 is retained at the nuclear envelope through its interaction with Bqt4, as the loss of Bqt4 results in the exclusive accumulation of Lem2 to the spindle pole body. An N-terminal nucleoplasmic region of Lem2 bears affinity to both Bqt4 and the SPB in a competitive manner. | 29292846 |
| 2018-03-26 11:23:00 | Lem2 and Man1 proteins of the fission yeast Schizosaccharomyces pombe perform fundamental functions of the animal cell lamina [Lem2][Man1] | 22540024 |
| 2017-02-18 12:15:00 | A combination of mutations in Lem2 and Bqt4, which encodes a nuclear membrane protein that anchors telomeres to the nuclear membrane, caused synthetic lethality. These genetic interactions imply that Lem2 cooperates with the nuclear membrane protein network to regulate genome stability | 27334362 |
| 2016-05-21 12:37:00 | in Schizosaccharomyces pombe, the nuclear membrane protein Lem2 associates with chromatin and mediates silencing and heterochromatin localization | 26744419 |
| Type | IDs |
|---|---|
| Synonymous | heh1 |
| Gene |
UniProtKB-ID:
LEM2_SCHPO
UniprotKB:
Q10109
UniParc:
UPI000013A149
EMBL:
CU329670
EnsemblGenome:
SPAC18G6.10
KO:
spo:SPAC18G6.10
|
| Nucleutide sequences |
EMBL-CDS:
CAA92388.1
Gene_ORFName:
SPAC18G6.10
EnsemblGenome_TRS:
SPAC18G6.10.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPAC18G6.10.1:pep
RefSeq:
NP_593673.1
|
| Others |
UniRef100:
UniRef100_Q10109
UniRef90:
UniRef90_Q10109
UniRef50:
UniRef50_Q10109
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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