| Type | Description |
|---|---|
| Definition | telomere-protecting protein |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:34:00 | A novel dual-function regulatory motif within Tpz1 unctions redundantly with Lys242 SUMOylation to promote telomere association of the Stn1-Ten1 complex, protecting telomeres, and counteracting TEL-patch-dependent telomerase activation to limit telomere extension. | 31396577 |
| 2017-10-07 12:21:00 | Together, these data provide a first glimpse into the architectural design of the Ccq1-Tpz1-Poz1 complex and reveals unique interactions that are important in maintaining the Schizosaccharomyces pombe telomere in a non-extendible state. | 28807855 |
| 2016-07-16 10:17:00 | The conservation between fission yeast Tpz1-Pot1 and human TPP1-POT1 interactions resulted in mapping a human melanoma-associated POT1 mutation (A532P) to the TPP1-POT1 interface. | 26365187 |
| 2016-04-30 10:58:00 | Tpz1-Ccq1 interaction is required for Ccq1 Thr93 phosphorylation and telomerase recruitment. | 25330395 |
| 2015-04-04 10:45:00 | SUMO inhibits telomerase through stimulation of Stn1/Ten1 action by Tpz1. | 24925530 |
| Type | IDs |
|---|---|
| Synonymous | SPAC6F6.18c, mug169 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001342857.1
|
| Others |
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员