| Type | Description |
|---|---|
| Definition | telomere length regulator |
| Date | Results | Publications |
|---|---|---|
| 2020-01-11 11:35:00 | Fission yeast cells lacking shelterin components Taz1 or Rap1 showed higher gross chromosomal rearrangements (GCRs) rates compared to wild-type, accumulating large chromosome deletions. Study results highlight unappreciated functions of the shelterin components Taz1 and Rap1 in maintaining genome stability, specifically by preventing non-telomeric GCRs. | 31454352 |
| 2019-07-13 11:34:00 | Telosome formation depends on the conserved telomeric proteins Taz1 and Rap1, and RNA. The lack of a detectable telosome in the absence of Taz1 indicates that Taz1 is required for telosome formation or integrity. Taz1 and Rap1 act together in organizing the telosome. | 29992245 |
| 2019-04-20 12:03:00 | The results suggest that Taz1 suppresses replication initiation through shelterin-mediated telomeric association of the origins at the onset of S phase. | 29997179 |
| 2018-04-28 12:02:00 | Genetic screens for identifying cis- and trans-acting factors creating heterochromatin-euchromatin boundaries showed unexpected properties for Rif1 and Taz1. Most cis-acting elements identified came from genomic loci bound by Taz1 and associated with origins of replication repressed by Taz1 and Rif1. Boundary formation by these elements required Taz1 and Rif1 and coincided with altered replication timing. | 28096402 |
| 2017-08-26 11:32:00 | Taz1-Shelterin promotes facultative heterochromatin assembly at chromosome-internal sites containing late replication origins. | 27264871 |
| Type | IDs |
|---|---|
| Synonymous | myb, myb1 |
| Gene |
UniProtKB-ID:
TAZ1_SCHPO
UniprotKB:
P79005
UniParc:
UPI0000136961
EMBL:
Y09406,
CU329670
EnsemblGenome:
SPAC16A10.07c
KO:
spo:SPAC16A10.07c
|
| Nucleutide sequences |
EMBL-CDS:
CAA70568.1,
CAB10000.1
Gene_ORFName:
SPAC16A10.07c
EnsemblGenome_TRS:
SPAC16A10.07c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPAC16A10.07c.1:pep
RefSeq:
NP_594047.1
|
| Others |
UniRef100:
UniRef100_P79005
UniRef90:
UniRef90_P79005
UniRef50:
UniRef50_P79005
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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