| Type | Description |
|---|---|
| Definition | Smc5-6 complex non-SMC subunit 2 |
| Date | Results | Publications |
|---|---|---|
| 2011-08-27 10:07:00 | role in protecting genome stability against spontaneous Top1-mediated DNA damage | 21408210 |
| 2010-01-21 00:00:00 | Nse2-dependent sumoylation activity has a role in DNA damage responses but not in the essential function of the Smc5-6 complex. [Nse2] | 15601841 |
| 2005-04-11 13:00:00 | Nse1 and Nse2 are non-SMC subunits of the Smc5-6 DNA repair complex. They both interact with Smc5. Nse1 and Nse2 function together with Rhp51 in the homologous recombination repair of DNA double-strand breaks. They are essential proteins. [Nse2] | 12966087 |
| 2005-04-11 13:00:00 | Nse1, Nse2, and Nse3 are crucial for meiosis. They also play an important role in mitigating the genome destabilizing effects of replication fork stalling. [Nse2] | 15331764 |
| Type | IDs |
|---|---|
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
NP_001343015.1
|
| Others |
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 23936535 |
PLoS One Roland Steinacher , Fekret Osman , Alexander Lorenz , Claire Bryer , Matthew C Whitby |
2013-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21444718 |
DNA repair and global sumoylation are regulated by distinct Ubc9 noncovalent complexes. Mol Cell Biol John Prudden , J Jefferson P Perry , Minghua Nie , Ajay A Vashisht , Andrew S Arvai , Chiharu Hitomi , Grant Guenther , James A Wohlschlegel , John A Tainer , Michael N Boddy |
2011-06-01 | - |
| 21408210 |
PLoS Genet. Johanna Heideker , John Prudden , J Jefferson P Perry , John A Tainer , Michael N Boddy |
2011-03-01 |
tdp1,
top1,
slx8,
rad60,
swi10,
nse2,
rad32,
rhp51
|
| 19528228 |
Smc5-Smc6-dependent removal of cohesin from mitotic chromosomes. Mol Cell Biol Emily A Outwin , Anja Irmisch , Johanne M Murray , Matthew J O'Connell |
2009-08-01 | - |
| 18031226 |
The role of Schizosaccharomyces pombe SUMO ligases in genome stability. Biochem Soc Trans F Z Watts , A Skilton , J C-Y Ho , L K Boyd , M A M Trickey , L Gardner , F-X Ogi , E A Outwin |
2007-12-01 | - |
| 17209013 |
Role of SUMO in the dynamics of telomere maintenance in fission yeast. Proc. Natl. Acad. Sci. U.S.A. Blerta Xhemalce , Eva Madi Riising , Peter Baumann , Anne Dejean , Benoît Arcangioli , Jacob-S Seeler |
2007-01-16 |
pku70,
tel1,
swi1,
pli1,
rad50,
rif1,
nse2,
pot1,
pol1
|
| 16823372 |
Nat. Biotechnol. Akihisa Matsuyama , Ritsuko Arai , Yoko Yashiroda , Atsuko Shirai , Ayako Kamata , Shigeko Sekido , Yumiko Kobayashi , Atsushi Hashimoto , Makiko Hamamoto , Yasushi Hiraoka , Sueharu Horinouchi , Minoru Yoshida |
2006-07-01 |
sum3,
ers1,
SPCC126.01c,
SPCC777.03c,
gst1,
SPCC569.06,
SPCC1442.02,
SPCC645.13,
hif2,
SPCC613.08,
mde7,
SPCC663.10,
tmp1,
xap5,
spf30,
SPCC1682.09c,
rpl3702,
bio2,
SPCC4B3.06c,
fta4,
mms2,
adn3,
imt2,
ste6,
SPCC825.02,
arg1,
prp28,
tpi1,
ctr4,
SPCC663.08c,
ade6,
SPCC70.10,
SPCC338.06c,
ynd1,
alr1,
mpg1,
cnd2,
SPCC965.04c,
SPCC132.01c,
SPCC1672.11c,
SPCC1442.07c,
SPCC830.11c,
SPCC1281.06c,
nup186,
SPCC1795.10c,
skb15,
ppe1,
SPCC14G10.01,
rad16,
SPCC622.02,
set1,
mis18,
SPCC1906.02c,
urm1,
SPCC306.08c,
get4,
ura4,
sgf73,
coq3,
oca8,
ssb3,
SPCC1494.06c,
not2,
SPCC569.07,
SPCC1840.07c,
ssb2,
meu15,
SPCC1450.10c,
tim23,
SPCC1672.01,
SPCC830.06,
bis1,
vtc4,
cid2,
ipk1,
srp72,
SPCP1E11.10,
sec59,
apn1,
SPCC63.06,
lat1,
rpm1,
SPCC5E4.05c,
kap113,
SPCC13B11.04c,
SPCC757.11c,
lsm2,
mug163,
SPCC1840.09,
cox13,
SPCPB16A4.05c,
SPCC285.03,
mug112,
SPCC330.03c,
SPCC622.11,
mrpl31,
SPCC777.17c,
rpl3402,
rpb3
|
| 16478984 |
The Nse5-Nse6 dimer mediates DNA repair roles of the Smc5-Smc6 complex. Mol. Cell. Biol. Stephanie Pebernard , James Wohlschlegel , W Hayes McDonald , John R Yates , Michael N Boddy |
2006-03-01 |
mus81,
smc6,
chk1,
nse3,
nse1,
rhp18,
uve1,
swi5,
rad3,
rad60,
nse5,
rad13,
nse6,
smc5,
rqh1,
nse2,
rhp51,
rhp55,
nse4
|
| 15601840 |
Composition and architecture of the Schizosaccharomyces pombe Rad18 (Smc5-6) complex. Mol. Cell. Biol. John Sergeant , Elaine Taylor , Jan Palecek , Maria Fousteri , Emily A Andrews , Sara Sweeney , Hideo Shinagawa , Felicity Z Watts , Alan R Lehmann |
2005-01-01 |
smc6,
nse3,
nse1,
smc5,
nse2,
nse4,
SMC5,
SMC6
|
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