| Type | Description |
|---|---|
| Definition | ring finger protein 169 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-10 13:01:00 | A comprehensive proteomics-based interaction screen that links DYRK1A to RNF169 and to the DNA damage response. | 30979931 |
| 2018-10-06 10:24:00 | results highlight the interplay of RNF169 with 53BP1 in fine-tuning choice of DSB repair pathways. | 30104380 |
| 2018-05-19 11:15:00 | USP7 is RNF169 interacting protein.Expression of USP7 and RNF169 positively correlated in breast cancer. | 28325877 |
| 2018-02-10 10:33:00 | The authors establish that RNF169 binds to ubiquitylated histone H2A-Lys13/Lys15 in a manner that involves its canonical ubiquitin-binding helix and a pair of arginine-rich motifs that interact with the nucleosome acidic patch. | 28406400 |
| 2017-09-09 10:38:00 | Ubiquitin ligases RNF168, RNF169, and RAD18 specifically bind histone H2A Lys13/15-ubiquitylated nucleosomes. 53BP1 chromatin recruitment may be activated by RNF168 and blocked by RNF169 and RAD18. | 28506460 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
RN169_HUMAN
UniprotKB:
Q8NCN4
UniParc:
UPI00001C1F15
EMBL:
AB082522,
BX640750
Ensembl:
ENSG00000166439
KO:
hsa:254225
|
| Nucleutide sequences |
EMBL-CDS:
CAE45858.1,
BAC02700.1
Ensembl_TRS:
ENST00000299563
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000299563
RefSeq:
XP_011543191.1,
NP_001092108.1
|
| Others |
UniRef100:
UniRef100_Q8NCN4
UniRef90:
UniRef90_Q8NCN4
UniRef50:
UniRef50_Q8NCN4
UniGene:
Hs.370145,
Hs.745050
CCDS:
CCDS41691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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