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2541633 swi6

2541633

swi6

chromodomain protein Swi6

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition chromodomain protein Swi6

研究结论

Date Results Publications
2021-02-13 13:24:00 TORC1 regulates G1/S transition and cell proliferation via the E2F homologs MBF and SBF in yeast. 32553629
2020-03-28 12:04:00 results indicate that Swi6 couples its oligomerization to the phase separation of chromatin by a counterintuitive mechanism, namely the dynamic exposure of buried nucleosomal regions; such reshaping of the octamer core by Swi6 increases opportunities for multivalent interactions between nucleosomes, thereby promoting phase separation; this mechanism may more generally drive chromatin organization beyond heterochromatin 31618757
2019-12-28 12:08:00 Swi6 interacts with Dfp1, a regulatory subunit of DBF4-dependent kinase (DDK), and failure to recruit Dfp1 to the pericentromere results in late DNA replication. 31000521
2019-03-23 11:44:00 The mechanism has been uncovered by which fission yeast heterochromatin protein Swi6 (mammalian HP1-homolog) prevents recruitment of activators of meiotic double-stranded breaks formation. 30078721
2017-12-02 12:15:00 findings uncover quantitative differences in how Swi6 and Chp2 interact with nucleosomal and non-nucleosomal ligands and qualitative differences in how their assembly on nucleosomes is regulated 28942089

名称对应

Type IDs
Synonymous SPAC824.10c
Gene
UniProtKB-ID: SWI6_SCHPO
UniprotKB: P40381
UniParc: UPI00001362A2
EMBL: CU329670, X71783
EnsemblGenome: SPAC664.01c
KO: spo:SPAC664.01c
Nucleutide sequences
EMBL-CDS: CAB57340.1, CAA50668.1
Gene_ORFName: SPAC664.01c, SPAC824.10c
EnsemblGenome_TRS: SPAC664.01c.1
Protein sequencees
EnsemblGenome_PRO: SPAC664.01c.1:pep
RefSeq: NP_593449.1
Others
UniRef100: UniRef100_P40381
UniRef90: UniRef90_P40381
UniRef50: UniRef50_P40381

全选

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研究热度

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