| Type | Description |
|---|---|
| Definition | Smc5-6 complex SMC subunit Smc5 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 10:15:00 | Authors show that the chromatin association and SUMO ligase activity of Smc5-Smc6 require the Nse5-Nse6 heterodimer, explaining how this nonessential cofactor critically supports the DNA repair roles of Smc5-Smc6. | 30348841 |
| 2019-07-20 11:04:00 | I summarize new research that is beginning to tease out the molecular details of Smc5/6 structure and function, knowledge that will illuminate the nuclear activities of Smc5/6 in the stability and dynamics of eukaryotic genomes | 30476445 |
| 2018-11-24 12:20:00 | Study shows that the Smc5/6-hinge complex binds preferentially to ssDNA and that this interaction is affected by both 'latch' and 'hub' mutations, suggesting a key role for these unique features in controlling DNA association by the Smc5/6 complex. | 28134253 |
| 2016-12-17 10:39:00 | The function of the SMC5/6 complex and its mammalian homologs in the cell cycle has not been clarified yet. | 26743946 |
| 2012-04-14 10:29:00 | Smc5 is a required for homologous recombination in S. pombe. | 21976700 |
| Type | IDs |
|---|---|
| Synonymous | spr18 |
| Gene |
UniProtKB-ID:
SMC5_SCHPO
UniprotKB:
O13710
UniParc:
UPI000228F382
EMBL:
CU329670,
AJ277543
EnsemblGenome:
SPAC14C4.02c
KO:
spo:SPAC14C4.02c
|
| Nucleutide sequences |
EMBL-CDS:
CAB11195.2,
CAB89122.1
Gene_ORFName:
SPAC14C4.02c
EnsemblGenome_TRS:
SPAC14C4.02c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPAC14C4.02c.1:pep
RefSeq:
NP_594907.2
|
| Others |
UniRef100:
UniRef100_O13710
UniRef90:
UniRef90_O13710
UniRef50:
UniRef50_O13710
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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