Type | Description |
---|---|
Definition | putative protein Fft3 |
Date | Results | Publications |
---|---|---|
2020-07-04 12:10:00 | Results found that Fft3 is important for DNA repair and is needed for single-strand annealing of an induced double-strand break. Furthermore, an inducible replication fork barrier system shows that Fft3 has two distinct roles at blocked DNA replication forks. First, Fft3 is needed for the resection of nascent strands, and second, it is required to restart the blocked forks independently of its ATPase activity. | 31575705 |
2018-12-01 12:10:00 | Data indicate Fun30(Fft3) as a chromatin remodeller, which localizes at transcribing regions to promote RNA polymerase II (RNAPII) transcription. | 28218250 |
2018-11-10 12:00:00 | These analyses of the regulation of nucleosome dynamics by Fun30(Fft3) during RNA polymerase II (RNAPII) -mediated transcription reveal an unprecedented role for a chromatin remodeler in nucleosome disassembly at transcribing regions. They offer a new conceptual framework that can describe, in mathematical terms, how nucleosome dynamics are controlled during RNAPII-mediated elongation. | 28925811 |
2017-09-09 14:43:00 | This work uncovers a conserved factor critical for epigenetic inheritance of heterochromatin and describes a mechanism in which Fft3 suppresses nucleosome turnover, preventing formation of structural barriers that impede replication at fragile regions in the genome. | 28318821 |
2016-01-02 11:00:00 | We propose that Fft3 has a global role in mediating association between specific chromatin domains and the nuclear envelope | 25798942 |
Type | IDs |
---|---|
Synonymous | snf2SR |
Gene |
UniProtKB-ID:
FFT3_SCHPO
UniprotKB:
O42861
UniParc:
UPI000006B5BE
EMBL:
AB027947,
CU329670
EnsemblGenome:
SPAC25A8.01c
KO:
spo:SPAC25A8.01c
|
Nucleutide sequences |
EMBL-CDS:
CAA16951.1,
BAA87251.1
Gene_ORFName:
SPAC25A8.01c
EnsemblGenome_TRS:
SPAC25A8.01c.1
|
Protein sequencees |
EnsemblGenome_PRO:
SPAC25A8.01c.1:pep
RefSeq:
NP_593617.1
|
Others |
UniRef100:
UniRef100_O42861
UniRef90:
UniRef90_O42861
UniRef50:
UniRef50_O42861
|
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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