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2541251 dsc1

2541251

dsc1

putative ubiquitin-protein ligase E3

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition putative ubiquitin-protein ligase E3

研究结论

Date Results Publications
2017-10-21 10:54:00 Data suggest that cdc48 cofactor ufd1 is required for SREBP1/2 cleavage/activation but does not interact with cdc48-rbd2 complex; cdc48-ufd1 is instead required at step prior to rbd2 function, during Golgi localization of dsc1-E3 ligase. (cdc48 = AAA family ATPase cdc48; ufd1 = cdc48-ufd1-npl4 complex component ufd1; dsc1-E3 ligase = ubiquitin-protein ligase E3; SREBP1/2 = sterol regulatory element binding proteins 1/2) 28821619
2015-08-29 10:19:00 Dsc1 is an active E3 ligase; loss of Dsc E3 ligase activity leads to endoplasmic reticulum localization of the Dsc complex. 25918164

名称对应

Type IDs
Gene
UniProtKB-ID: DSC1_SCHPO
UniprotKB: O43085
UniParc: UPI000228F3B3
EMBL: CU329671
EnsemblGenome: SPBC947.10
KO: spo:SPBC947.10
Nucleutide sequences
EMBL-CDS: CAA17038.2
Gene_ORFName: SPBC947.10
EnsemblGenome_TRS: SPBC947.10.1
Protein sequencees
EnsemblGenome_PRO: SPBC947.10.1:pep
RefSeq: NP_595266.2
Others
UniRef100: UniRef100_O43085
UniRef90: UniRef90_O43085
UniRef50: UniRef50_O43085

全选

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研究热度

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