Type | Description |
---|---|
Definition | DNA repair and recombination protein |
Date | Results | Publications |
---|---|---|
2020-04-18 11:35:00 | The unwinding of double-stranded DNA by Pif1 is dominated by highly processive and repetitive attempts of partial DNA opening. | 31744872 |
2019-07-13 10:59:00 | The nuclear isoform of Pfh1 (nPfh1) unwound RNA/DNA hybrids more efficiently than DNA/DNA. Pfh1 resolves RNA/DNA structures like R-loops in vivo. nPfh1 displaced proteins from DNA and possessed strand-annealing activity. The unwinding and protein displacement activities were dependent on the Pif1 signature motif. nPfh1-L430P and nPfh1-Delta21 still displayed binding to G-quadruplex DNA and strand-annealing. | 30053106 |
2017-06-24 11:39:00 | The nuclear isoform of Pfh1 (nPfh1) unwound both types of structure, and although the G4-stabilizing compound Phen-DC3 significantly enhanced their stability, nPfh1 still resolved them efficiently | 27185885 |
2017-05-20 11:52:00 | In budding and fission yeasts, Pif1 family helicases impact both telomerase-mediated and semi-conservative replication of telomeric DNA as well as recombination-mediated telomere lengthening. (Review) | 27233114 |
2017-05-13 13:33:00 | Pfh1 is an accessory DNA helicase that interacts with the replisome and promotes replication and suppresses DNA damage at hard-to-replicate sites. | 27611590 |
Type | IDs |
---|---|
Synonymous | pif1 |
Gene |
UniProtKB-ID:
PIF1_SCHPO
UniprotKB:
Q9UUA2
UniParc:
UPI0003994EA9,
UPI0000131AA0
EMBL:
AF074944,
CU329671
EnsemblGenome:
SPBC887.14c
KO:
spo:SPBC887.14c
|
Nucleutide sequences |
EMBL-CDS:
CAA21899.1,
AAC26139.1
Gene_ORFName:
SPBC887.14c
EnsemblGenome_TRS:
SPBC887.14c.1
|
Protein sequencees |
EnsemblGenome_PRO:
SPBC887.14c.1:pep
RefSeq:
NP_596488.1
|
Others |
UniRef100:
UniRef100_Q9UUA2
UniRef90:
UniRef90_Q9UUA2
UniRef50:
UniRef50_Q9UUA2
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
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Refseq |
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