| Type | Description |
|---|---|
| Definition | collagen type II alpha 1 chain |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:31:00 | Gene expression of type II collagen is regulated by direct interaction with Kruppel-like factor 4 and AT-rich interactive domain 5B. | 33383116 |
| 2019-08-31 10:17:00 | Induction of OA caused downregulation of Col2a1. Expression of Col2a1 showed upregulation in therapeutic group with separate administration chondroitin sulfate or a probiotic diet and the cumulative effects in case of co-administration. | 30938133 |
| 2019-06-22 10:17:00 | E1 and E2 enhancer activities in type II collagen and aggrecan are regulated through distinct epigenetic modifications by histone deacetylase 10 and sirtuin 6. | 30981839 |
| 2017-06-03 10:55:00 | These findings suggest a novel mechanism of action of SOX5/6; namely, the SOX9/5/6 combination enhances Col2a1 transcription through a novel enhancer in intron 6 together with the enhancer in intron 1. | 27881681 |
| 2016-06-28 10:27:00 | The ERK1/2 and Smad2/3 signaling pathways regulate type II collagen and aggrecan expression in rat chondrocytes. | 26165845 |
| Type | IDs |
|---|---|
| Synonymous | CG2A1A, COLLII |
| Gene |
UniProtKB-ID:
CO2A1_RAT
UniprotKB:
P05539
UniParc:
UPI00000E8948
EMBL:
L48440,
M10613,
K02804,
X79816
KO:
rno:25412
|
| Nucleutide sequences |
EMBL-CDS:
AAA79780.1,
AAA40919.1,
CAA56213.1,
AAA40920.1
|
| Protein sequencees |
RefSeq:
NP_037061.1,
XP_006242370.1
|
| Others |
UniRef100:
UniRef100_P05539
UniRef90:
UniRef90_P02458
UniRef50:
UniRef50_P02458
UniGene:
Rn.10124
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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