| Type | Description |
|---|---|
| Definition | 2-oxoglutarate and Fe(2+) dioxygenase domain-containing protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-26 11:20:00 | hydroxylase Ofd1 regulates the Sre1 hypoxic transcription factor in fission yeast by controlling DNA binding.[Sre1; ofd1] | 22017871 |
| 2018-03-26 10:59:00 | The Ofd1 N-terminal dioxygenase domain is required for oxygen sensing and the Ofd1 C-terminal domain accelerates Sre1N degradation.(Sre1)(Ofd1) | 18418381 |
| 2013-03-09 11:02:00 | Data indicate that when oxygen is present, the prolyl hydroxylase Ofd1 down-regulates sterol regulatory element-binding protein Sre1N activity in two ways: first, by inhibiting its binding to DNA, and second, by accelerating its degradation. | 22833559 |
| 2011-08-06 11:13:00 | Studies indicate that the Nro1 NTD binds Ofd1CTDD and stabilizes Sre1N. | 21481773 |
| 2010-01-21 00:00:00 | Ofd1 dioxygenase domain functions as an oxygen sensor that regulates binding of Nro1 to Ofd1 to control oxygen-dependent Sre1N stability. | 19158663 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
OFD1_SCHPO
UniprotKB:
Q11120
UniParc:
UPI000006C861
EMBL:
D83659,
CU329671
EnsemblGenome:
SPBC6B1.08c
KO:
spo:SPBC6B1.08c
|
| Nucleutide sequences |
EMBL-CDS:
CAA17051.1,
BAA12034.1
Gene_ORFName:
SPBC6B1.08c
EnsemblGenome_TRS:
SPBC6B1.08c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC6B1.08c.1:pep
RefSeq:
NP_596087.1
|
| Others |
UniRef100:
UniRef100_Q11120
UniRef90:
UniRef90_Q11120
UniRef50:
UniRef50_Q11120
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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