| Type | Description |
|---|---|
| Definition | DNA repair protein |
| Date | Results | Publications |
|---|---|---|
| 2019-05-18 12:01:00 | The authors find that the 53BP1 orthologue Crb2 and Rev7 specifically repress long-range resection through the RecQ helicase-dependent pathway, thereby preventing hyper-resection. | 29697047 |
| 2014-09-06 10:52:00 | The data supports a model such that elevated Cdc2 activity delays the transition of Crb2 from its G1 to its G2 mode by blocking Srs2 DNA helicase and Casein Kinase 1 (Hhp1). | 24861625 |
| 2012-09-29 11:07:00 | These results suggest that the main role of Crb2 in DNA damage checkpoint signaling is recruiting Chk1 to sites of DNA lesions. | 22792081 |
| 2010-11-27 11:00:00 | Findings argue that binding of the Crb2 BRCT repeats to pH2AX is critical for checkpoint activity and provide new insight into the mechanisms of chromatin-mediated genome stability. | 20679488 |
| 2010-11-27 11:00:00 | Data show that polar interactions of Crb2 serine-548 and lysine-619 with the phosphate group of phospho-H2A (gamma-H2A) are critical for Crb2 IRIF formation and checkpoint function. | 20679485 |
| Type | IDs |
|---|---|
| Synonymous | rhp9 |
| Gene |
UniProtKB-ID:
RHP9_SCHPO
UniprotKB:
P87074
UniParc:
UPI00001338AA
EMBL:
Y09431,
D86478,
CU329671
EnsemblGenome:
SPBC342.05
KO:
spo:SPBC342.05
|
| Nucleutide sequences |
EMBL-CDS:
CAB46775.1,
CAA70582.1,
BAA13093.1
Gene_ORFName:
SPBC342.05
EnsemblGenome_TRS:
SPBC342.05.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC342.05.1:pep
RefSeq:
NP_596748.1
|
| Others |
UniRef100:
UniRef100_P87074
UniRef90:
UniRef90_P87074
UniRef50:
UniRef50_P87074
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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