| Type | Description |
|---|---|
| Definition | histone H3 methyltransferase Clr4 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:46:00 | N-Terminus Does Not Govern Protein Turnover of Schizosaccharomyces pombe CENP-A. | 32859127 |
| 2020-01-11 10:39:00 | Clr4 chromodomain binds the H3K9me3 tail. Both the chromodomain and the disordered region connecting the chromodomain and the SET domain bind the nucleosome core. Interaction of the disordered region with the nucleosome core is independent of H3K9me and contributes to H3K9me in vitro and in vivo. Those interactions with the nucleosome core contribute to de novo H3K9me deposition and to heterochromatin establishment. | 31165882 |
| 2019-02-23 13:08:00 | revelation of an autoinhibited conformation in the conserved H3K9 methyltransferase Clr4 (also known as Suv39h) of the fission yeast Schizosaccharomyces pombe that has a critical role in preventing aberrant heterochromatin formation | 30051891 |
| 2017-09-09 11:43:00 | Survival in quiescence requires the euchromatic deployment of Clr4 by Ago1-associated small RNAs. | 27984744 |
| 2015-05-02 10:09:00 | These results demonstrate how a direct "read-write" mechanism involving Clr4 propagates histone modifications and allows histones to act as carriers of epigenetic information. | 25831549 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
CLR4_SCHPO
UniprotKB:
O60016
UniParc:
UPI0000127B94
EMBL:
AF061854,
AJ007840,
CU329671
EnsemblGenome:
SPBC428.08c
KO:
spo:SPBC428.08c
|
| Nucleutide sequences |
EMBL-CDS:
CAA07709.1,
AAC18302.1,
CAA22283.1
Gene_ORFName:
SPBC428.08c
EnsemblGenome_TRS:
SPBC428.08c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC428.08c.1:pep
RefSeq:
NP_595186.1
|
| Others |
UniRef100:
UniRef100_O60016
UniRef90:
UniRef90_O60016
UniRef50:
UniRef50_O60016
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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