| Type | Description |
|---|---|
| Definition | DNA polymerase epsilon catalytic subunit Pol2 |
| Date | Results | Publications |
|---|---|---|
| 2013-03-09 10:24:00 | Disruption of Dos1, Dos2, or Cdc20 results in dissociation of CENP-A from centromeres and mislocalization of the protein to noncentromeric sites during S phase. | 23267073 |
| 2012-12-29 11:40:00 | Cdc20 and Dpb2 of the Pol epsilon complex are required for loading of GINS, Cut5, Drc1, and Cdc45 onto replication origins. | 22718908 |
| 2012-03-03 11:14:00 | Collectively, these data and earlier results in budding yeast indicate that the major roles of Pol-delta and Pol-epsilon at the eukaryotic replication fork are evolutionarily conserved. | 22144917 |
| 2010-01-21 00:00:00 | GINS functions in a pathway that involves Cdc45 and is necessary for DNA polymerase epsilon chromatin binding, but a separate pathway sets up the chromatin association of DNA polymerase alpha. | 19109429 |
| 2010-01-21 00:00:00 | the Mad3 KEN box is a critical mediator of Cdc20-APC/C inhibition, without which neither Mad3 nor Mad2 can associate with the APC/C or inhibit anaphase onset | 18556659 |
| Type | IDs |
|---|---|
| Synonymous | pol2 |
| Gene |
UniProtKB-ID:
DPOE_SCHPO
UniprotKB:
P87154
UniParc:
UPI00001297C8
EMBL:
CU329671,
D89223
EnsemblGenome:
SPBC25H2.13c
KO:
spo:SPBC25H2.13c
|
| Nucleutide sequences |
EMBL-CDS:
BAA13884.1,
CAB08772.1
Gene_ORFName:
SPBC25H2.13c
EnsemblGenome_TRS:
SPBC25H2.13c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC25H2.13c.1:pep
RefSeq:
NP_596354.1
|
| Others |
UniRef100:
UniRef100_P87154
UniRef90:
UniRef90_P87154
UniRef50:
UniRef50_P87154
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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