Type | Description |
---|---|
Definition | spindle checkpoint protein Mad2 |
Date | Results | Publications |
---|---|---|
2017-03-11 12:38:00 | Results provide evidence that the truncation of two beta strands (beta7 and beta8) of Mad2 destabilize the safety belt and affect the Cdc20-Mad2 interaction leading to defects in the spindle checkpoint activation. | 27664031 |
2012-08-18 10:18:00 | A kinase-dead allele of the fission yeast MPS1 homolog (Mph1) is checkpoint defective and levels of anaphase promoting complex-associated Mad2 and Mad3 are dramatically reduced in this mutant. | 22281223 |
2010-01-21 00:00:00 | findings indicate that altered Mad2p anaphase spindle localizations can reflect changes in spindle function during mitotic exit that could contribute to fidelity in anaphase events | 16855399 |
2010-01-21 00:00:00 | Mad2p and Slp1p act downstream of Rad3p in the DNA replication checkpoint and Mad2p is required for the DNA replication checkpoint when Cds1p is compromised | 15347659 |
2010-01-21 00:00:00 | the Mad3 KEN box is a critical mediator of Cdc20-APC/C inhibition, without which neither Mad3 nor Mad2 can associate with the APC/C or inhibit anaphase onset | 18556659 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
MAD2_SCHPO
UniprotKB:
O14417
UniParc:
UPI000012EB16
EMBL:
CU329671,
U72150
EnsemblGenome:
SPBC20F10.06
KO:
spo:SPBC20F10.06
|
Nucleutide sequences |
EMBL-CDS:
CAA16846.1,
AAB68597.1
Gene_ORFName:
SPBC20F10.06
EnsemblGenome_TRS:
SPBC20F10.06.1
|
Protein sequencees |
EnsemblGenome_PRO:
SPBC20F10.06.1:pep
RefSeq:
NP_596370.1
|
Others |
UniRef100:
UniRef100_O14417
UniRef90:
UniRef90_O14417
UniRef50:
UniRef50_O14417
|
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