例如:"NBL1", "4681", "drought"
收藏
2540589 mad2

2540589

mad2

spindle checkpoint protein Mad2

protein-coding

Schizosaccharomyces pombe

基因描述

Type Description
Definition spindle checkpoint protein Mad2

研究结论

Date Results Publications
2017-03-11 12:38:00 Results provide evidence that the truncation of two beta strands (beta7 and beta8) of Mad2 destabilize the safety belt and affect the Cdc20-Mad2 interaction leading to defects in the spindle checkpoint activation. 27664031
2012-08-18 10:18:00 A kinase-dead allele of the fission yeast MPS1 homolog (Mph1) is checkpoint defective and levels of anaphase promoting complex-associated Mad2 and Mad3 are dramatically reduced in this mutant. 22281223
2010-01-21 00:00:00 findings indicate that altered Mad2p anaphase spindle localizations can reflect changes in spindle function during mitotic exit that could contribute to fidelity in anaphase events 16855399
2010-01-21 00:00:00 Mad2p and Slp1p act downstream of Rad3p in the DNA replication checkpoint and Mad2p is required for the DNA replication checkpoint when Cds1p is compromised 15347659
2010-01-21 00:00:00 the Mad3 KEN box is a critical mediator of Cdc20-APC/C inhibition, without which neither Mad3 nor Mad2 can associate with the APC/C or inhibit anaphase onset 18556659

名称对应

Type IDs
Gene
UniProtKB-ID: MAD2_SCHPO
UniprotKB: O14417
UniParc: UPI000012EB16
EMBL: CU329671, U72150
EnsemblGenome: SPBC20F10.06
KO: spo:SPBC20F10.06
Nucleutide sequences
EMBL-CDS: CAA16846.1, AAB68597.1
Gene_ORFName: SPBC20F10.06
EnsemblGenome_TRS: SPBC20F10.06.1
Protein sequencees
EnsemblGenome_PRO: SPBC20F10.06.1:pep
RefSeq: NP_596370.1
Others
UniRef100: UniRef100_O14417
UniRef90: UniRef90_O14417
UniRef50: UniRef50_O14417

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员