| Type | Description |
|---|---|
| Definition | glutaredoxin Grx4 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-30 12:02:00 | Study aimed to biochemically define these protein-protein and protein-metal interactions. Grx4 was found to bind a [2Fe-2S] cluster with spectroscopic features similar to other CGFS glutaredoxins. Grx4 and Php4 also copurify as a complex with a [2Fe-2S] cluster that is spectroscopically distinct from the cluster on Grx4these results show that Grx4 controls Php4 function through binding of a bridging [2Fe-2S] cluster. | 28725905 |
| 2016-01-02 11:41:00 | Grx4 independently governs the Php4 and Fep1 repressors through metal transfer. total or partial disassembly of the Grx4-Fra2 cluster actively participates in iron-containing Fep1 activation | 25806539 |
| 2011-11-05 11:12:00 | Results describe the first example of a monothiol glutaredoxin (Grx4)that acts as an inhibitory partner for an iron-regulated transcription factor under conditions of low iron levels. | 21421748 |
| 2011-08-06 11:13:00 | These results suggest that the ability of Grx4 to bind iron, most likely Fe-S cofactor, could be critical in interacting with and modulating the activity of Fep1. | 21531205 |
| 2010-01-21 00:00:00 | Grx4 and Crm1 are novel components involved in the mechanism by which Php4 is inactivated by iron in a Fep1-independent manner. | 19502236 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GLRX4_SCHPO
UniprotKB:
O74790
UniParc:
UPI00000698B2
EMBL:
CU329671,
AY435094
EnsemblGenome:
SPBC26H8.06
KO:
spo:SPBC26H8.06
|
| Nucleutide sequences |
EMBL-CDS:
AAR08197.1,
CAA21098.1
Gene_ORFName:
SPBC26H8.06
EnsemblGenome_TRS:
SPBC26H8.06.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC26H8.06.1:pep
RefSeq:
NP_596647.1
|
| Others |
UniRef100:
UniRef100_O74790
UniRef90:
UniRef90_O74790
UniRef50:
UniRef50_O74790
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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