| Type | Description |
|---|---|
| Definition | dual-specificity protein kinase Mph1 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-26 11:22:00 | Phosphorylation of the conserved MELT motifs in Spc7 by Mph1 (Mps1) recruits Bub1 and Bub3 to the kinetochore and this is required to maintain the spindle assembly checkpoint signal. [Bub1; Bub3; Spc7; Mph1] | 22521786 |
| 2016-12-17 10:14:00 | The Ndc80 hairpin region might act as a platform for the kinetochore recruitment of Mph1. | 26900649 |
| 2013-06-01 10:29:00 | Our results highlight the crucial role of Mph1 at kinetochores and suggest that the Mad1-Mad2 complex does not necessarily need to be enriched at kinetochores for functional SAC signaling. | 22825872 |
| 2012-09-08 11:05:00 | MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit spindle assembly checkpoint proteins and promote chromosome alignment. | 22660415 |
| 2012-08-18 10:18:00 | A kinase-dead allele of the fission yeast MPS1 homolog (Mph1) is checkpoint defective and levels of anaphase promoting complex-associated Mad2 and Mad3 are dramatically reduced in this mutant. | 22281223 |
| Type | IDs |
|---|---|
| Synonymous | SPBC1271.16c, SPBC243.01 |
| Gene |
UniProtKB-ID:
MPH1L_SCHPO
UniprotKB:
O94235
UniParc:
UPI000012F46E
EMBL:
AF020705,
CU329671
EnsemblGenome:
SPBC106.01
KO:
spo:SPBC106.01
|
| Nucleutide sequences |
EMBL-CDS:
CAB72266.1,
AAD01648.1
Gene_ORFName:
SPBC106.01,
SPBC1271.16c,
SPBC243.01
EnsemblGenome_TRS:
SPBC106.01.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC106.01.1:pep
RefSeq:
NP_595150.2
|
| Others |
UniRef100:
UniRef100_O94235
UniRef90:
UniRef90_O94235
UniRef50:
UniRef50_O94235
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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